In the dynamic field of medicinal chemistry and drug discovery, peptide synthesis stands out as a cornerstone for developing novel therapeutics and research tools. At the heart of efficient and reliable peptide synthesis lies the quality of the building blocks employed. Among these, N-Boc-L-2-aminobutyric acid, identified by its CAS number 34306-42-8, plays a pivotal role. This article delves into its significance and provides insights for procurement managers and R&D scientists seeking to purchase this vital compound.

Understanding N-Boc-L-2-aminobutyric Acid (CAS 34306-42-8)

N-Boc-L-2-aminobutyric acid is a protected amino acid derivative. The tert-butyloxycarbonyl (Boc) group serves as a protecting group for the alpha-amino functionality. This protection is crucial during the stepwise assembly of peptide chains, preventing unwanted side reactions and ensuring regioselectivity. The inherent chirality of the L-isomer, combined with the Boc protection, makes it an indispensable reagent for synthesizing specific peptide sequences.

Why Choose This Intermediate for Peptide Synthesis?

The primary advantage of using N-Boc-L-2-aminobutyric acid in peptide synthesis is its contribution to the overall purity and yield of the final peptide product. As a pharmaceutical intermediate, its consistent quality and well-defined chemical properties are paramount. For B2B procurement, understanding its specifications is key. Typically, this compound presents as a light yellow powder with a purity of around 97%. Its melting point, generally between 70-74 °C, and solubility characteristics are vital data points for formulation scientists and process chemists.

Procurement Insights: Finding a Reliable Supplier

For any research and development or manufacturing operation, securing a consistent supply of high-quality raw materials is non-negotiable. When looking to buy N-Boc-L-2-aminobutyric acid, it's essential to partner with reputable manufacturers and suppliers. Many leading chemical companies, particularly those based in China, offer this product. When evaluating potential suppliers, consider factors such as product purity verification (e.g., HPLC data), batch-to-batch consistency, packaging options, storage recommendations, and competitive price points. Companies specializing in pharmaceutical intermediates and amino acid derivatives are often the best sources for reliable procurement.

Applications Beyond Peptide Synthesis

While its application in peptide synthesis is primary, N-Boc-L-2-aminobutyric acid also serves as a versatile building block in broader organic synthesis, particularly in the development of chiral drugs and complex organic molecules. Its protected amino acid structure makes it suitable for various coupling reactions and modifications.

Conclusion

The availability of high-quality N-Boc-L-2-aminobutyric acid is critical for advancements in pharmaceutical research and peptide-based drug development. By understanding its properties and the importance of sourcing from reliable manufacturers and suppliers, businesses can ensure the success of their synthesis projects. For those seeking to enhance their peptide production capabilities, exploring options to purchase this key intermediate is a strategic move. We, as a dedicated supplier of pharmaceutical intermediates, are here to meet your needs for this crucial component.