The incorporation of fluorine atoms into organic molecules has become a cornerstone of modern drug discovery and development. Fluorine's unique properties—high electronegativity, small atomic radius, and ability to form strong carbon-fluorine bonds—can dramatically influence a molecule's lipophilicity, metabolic stability, binding affinity, and overall pharmacokinetic profile. Among the various classes of fluorinated compounds, fluorinated pyridines are of particular interest due to the pyridine ring's inherent bioactivity and its frequent presence in therapeutic agents. Understanding the availability and application of specific fluorinated pyridines, such as 5-(3-Fluorophenyl)-2-methylpyridine (CAS: 713143-67-0), is vital for researchers and chemical procurement professionals.

5-(3-Fluorophenyl)-2-methylpyridine: A Valuable Fluorinated Building Block

5-(3-Fluorophenyl)-2-methylpyridine is a prime example of a strategically designed fluorinated pyridine intermediate. The presence of a fluorine atom on the phenyl ring can modulate electron distribution, alter pKa values, and enhance interactions with biological targets. In its own right, this compound is a key precursor in the synthesis of sophisticated pharmaceutical compounds, most notably Vorapaxar Sulfate (CAS:705260-08-8), an antiplatelet medication. The specific arrangement of the fluorophenyl group and the methyl substituent on the pyridine ring makes it an ideal starting material for complex synthetic routes.

Sourcing Strategies for Specialty Chemical Intermediates

For researchers and chemists looking to buy specialty intermediates like 5-(3-Fluorophenyl)-2-methylpyridine, effective sourcing is crucial:

  • Identify Specialist Suppliers: Look for chemical suppliers that focus on advanced intermediates and fine chemicals, particularly those with expertise in fluorinated compounds and heterocycles.
  • Verify Purity and Specifications: Always confirm that the product meets the required assay (e.g., ≥98.0%) and has consistent physical and chemical properties (e.g., boiling point 284.5ºC, density 1.111g/cm3).
  • Consider Manufacturers in Key Regions: China has emerged as a significant hub for chemical manufacturing, offering competitive pricing and robust production capabilities. Partnering with a reputable Chinese manufacturer can ensure a stable supply.
  • Inquire about Pricing and Bulk Discounts: Understanding the 5-(3-Fluorophenyl)-2-methylpyridine price is essential for budgeting. Suppliers often offer tiered pricing or discounts for larger quantities.

NINGBO INNO PHARMCHEM CO.,LTD.: Your Partner in Advanced Synthesis

At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing the chemical building blocks that drive innovation in drug discovery. Our portfolio includes high-purity fluorinated heterocycles like 5-(3-Fluorophenyl)-2-methylpyridine. We understand the importance of reliability, quality, and cost-effectiveness. If you are seeking to buy this critical intermediate for your research or manufacturing needs, we invite you to contact us. Discover the advantages of working with a trusted supplier in China who can provide the quality and consistency required for successful pharmaceutical development.