In the sophisticated domain of peptide synthesis, specific building blocks are indispensable for crafting peptides with targeted functionalities and structures. Fmoc-Asp-OAll, identified by its CAS number 144120-53-6, stands as a prime example of such a crucial reagent. This compound, chemically known as N-alpha-Fmoc-L-Aspartic Acid Alpha-Allyl Ester, is widely utilized in Fmoc solid-phase peptide synthesis (SPPS) due to its unique orthogonal protection scheme, which is vital for introducing modifications to the aspartic acid side chain. As a leading manufacturer and supplier, we provide this high-purity intermediate to researchers and industries globally.

The utility of Fmoc-Asp-OAll in SPPS is rooted in its dual protection strategy. The N-terminal alpha-amino group is protected by the base-labile Fmoc group, standard in the Fmoc SPPS protocol. Crucially, the beta-carboxyl group of the aspartic acid side chain is esterified with an allyl group. This allyl ester protection is orthogonal to the Fmoc group and commonly used acid-labile side chain protecting groups. It can be selectively cleaved using mild palladium-based reagents, which preserves other protecting groups on the peptide chain. This capability is essential for creating peptides with complex side-chain modifications or for specific conjugation strategies. The compound's physical form as a white powder and its recommended storage temperature of 2-8°C underscore its stability and ease of use for peptide chemists.

For researchers and R&D departments, sourcing high-quality Fmoc-Asp-OAll is a critical procurement decision. A reliable supplier ensures that the material meets strict purity standards, typically exceeding 98% by HPLC, which is non-negotiable for reproducible synthesis outcomes. We, as a prominent manufacturer and supplier based in China, are dedicated to delivering this intermediate with guaranteed quality and competitive pricing. If you are looking to buy this essential building block, partnering with us provides access to reliable, high-performance reagents for your peptide synthesis needs.

The application of Fmoc-Asp-OAll extends across various fields, including pharmaceutical research for developing peptide-based drugs, biochemical studies, and the creation of custom peptides for specific research purposes. Its role in enabling selective side-chain modification makes it a go-to reagent for scientists aiming for intricate molecular designs. Whether you require small quantities for laboratory experiments or larger volumes for production, our manufacturing capacity ensures a consistent supply chain. We encourage you to reach out to us to purchase Fmoc-Asp-OAll and benefit from our expertise as a trusted provider.

In summary, Fmoc-Asp-OAll (CAS 144120-53-6) is a highly specialized and valuable intermediate in the field of peptide synthesis. Its orthogonal protection strategy facilitates complex peptide modifications, making it a cornerstone reagent. We invite you to consider our offerings as a dependable source for this critical amino acid derivative, confident in our ability to supply the quality and reliability your research demands.