In the dynamic field of peptide synthesis, the choice of amino acid derivatives plays a pivotal role in the success of creating complex peptides. Among these crucial building blocks, Fmoc-D-4-Methoxyphenylalanine stands out. This article delves into its significance, properties, and applications for researchers and procurement managers seeking high-quality materials for their projects.

Fmoc-D-4-Methoxyphenylalanine, identified by CAS number 201335-88-8, is a protected D-amino acid derivative. The N-terminal Fmoc (9-fluorenylmethoxycarbonyl) group serves as a versatile protecting group, essential for stepwise peptide chain elongation using the Fmoc strategy in solid-phase peptide synthesis (SPPS). The inclusion of the D-configuration of methionine-substituted phenylalanine introduces unique structural characteristics to the resulting peptides, often conferring increased resistance to enzymatic degradation and altering pharmacokinetic profiles. This makes it a valuable component for developing more stable and potent peptide therapeutics.

As a leading manufacturer and supplier based in China, we understand the critical need for purity and consistency in biochemical reagents. Our Fmoc-D-4-Methoxyphenylalanine is typically supplied as a white to off-white powder with a purity of 97-98%, ensuring it meets the stringent requirements of advanced peptide synthesis protocols. When you buy this amino acid derivative from us, you are investing in quality that supports successful outcomes in research and development.

The applications for Fmoc-D-4-Methoxyphenylalanine are diverse, primarily within the pharmaceutical and biotechnology sectors. It is indispensable for:

  • Drug Discovery: Used in the synthesis of novel peptide-based drug candidates, where the D-amino acid component can improve stability and bioavailability. Researchers looking to explore new therapeutic avenues can find this a vital intermediate.
  • Peptide Therapeutics: Essential for developing therapeutic peptides designed for conditions requiring enhanced enzymatic resistance or specific conformational properties. Procuring this material from a reliable manufacturer ensures a consistent supply for clinical trial materials or commercial production.
  • Biochemical Research: Employed in fundamental research to understand peptide structure-activity relationships, protein folding, and enzyme interactions. Many academic institutions and research labs seek a trustworthy supplier for their ongoing studies.
  • Custom Peptide Synthesis: A key building block for custom peptide synthesis services, allowing for the creation of peptides with specific modifications and sequences tailored to client needs.

For procurement managers and R&D scientists, sourcing essential chemicals like Fmoc-D-4-Methoxyphenylalanine involves more than just price; it requires confidence in supply chain reliability and product quality. By choosing to purchase from our extensive catalog, you benefit from competitive pricing, a commitment to quality control, and direct access to a reputable Chinese manufacturer. We encourage you to request a quote for bulk quantities or explore our product specifications for your next peptide synthesis project.

The demand for specialized amino acid derivatives continues to grow as peptide science advances. Fmoc-D-4-Methoxyphenylalanine represents a critical component for innovation in pharmaceuticals and biotechnology. We are dedicated to supporting these advancements by providing high-quality chemical building blocks. Contact us today to learn more about our product offerings and how we can fulfill your chemical sourcing needs.