In the dynamic field of peptide synthesis, the selection of high-quality protected amino acids is paramount to achieving successful and reproducible outcomes. Among these, N-Cbz-L-Histidine stands out as a vital building block, enabling scientists and researchers to construct complex peptide sequences with precision and efficacy. As a leading chemical manufacturer and supplier, understanding the nuances of this compound is key to optimizing peptide-based research and development.

N-Cbz-L-Histidine, also known by its CAS number 14997-58-1, is a derivative of the essential amino acid L-Histidine, featuring a benzyloxycarbonyl (Cbz) protecting group on the alpha-amino nitrogen. This protection is crucial in peptide synthesis as it prevents the alpha-amino group from reacting prematurely during coupling steps, ensuring that the peptide bond forms exclusively between the carboxyl group of one amino acid and the amino group of the next. The resulting white powder is characterized by its high purity, often exceeding 98.5% as confirmed by HPLC analysis, a critical factor for any scientist looking to buy N-Cbz-L-Histidine for sensitive applications.

The imidazole side chain of histidine presents unique challenges and opportunities in peptide synthesis. The Cbz protection on the alpha-amino group, combined with careful handling of the side chain's reactivity, allows for the controlled incorporation of histidine into target peptides. This amino acid is particularly important due to histidine's role in enzymatic activity, metal binding, and buffering capabilities within peptides and proteins. Therefore, the availability of high-purity N-Cbz-L-Histidine supplier in China is a significant advantage for research institutions and pharmaceutical companies globally.

When sourcing this chemical intermediate, it is essential to consider the manufacturer's reputation and commitment to quality. A reliable supplier will provide detailed specifications, certificates of analysis, and consistent batch-to-batch quality. For those seeking to purchase N-Cbz-L-Histidine price information is often a key consideration, but should be balanced with purity and reliability. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to offering superior quality protected amino acids, ensuring that your research is supported by the finest raw materials. We understand the importance of timely delivery and competitive pricing for bulk orders, making us a preferred partner for your peptide synthesis projects.

In conclusion, N-Cbz-L-Histidine is an indispensable reagent in the realm of peptide synthesis. Its high purity, reliable sourcing from manufacturers, and precise application in constructing histidine-containing peptides underscore its importance. Researchers and procurement managers should prioritize quality and consistency when choosing a supplier to guarantee the success of their innovative projects.