In the complex world of pharmaceutical development, the quality and availability of key chemical intermediates are paramount. Among these essential building blocks is tert-Butyl N-(3-aminophenyl)carbamate (CAS No.: 68621-88-5), a compound that plays a significant role in the synthesis of various active pharmaceutical ingredients (APIs). Understanding its properties and applications is vital for R&D scientists, formulation specialists, and procurement managers involved in drug manufacturing.

Tert-Butyl N-(3-aminophenyl)carbamate, also known by synonyms such as N-Boc-m-Phenylenediamine, is characterized by its off-white powder appearance and a high purity level, typically exceeding 98.0%. This high assay is crucial for ensuring the efficiency and success of complex synthetic routes, minimizing unwanted side reactions, and ultimately contributing to the purity of the final API. Its chemical structure, featuring both an amino group and a protected amine, makes it a versatile intermediate for introducing specific functionalities into target molecules.

One of the most notable applications of tert-Butyl N-(3-aminophenyl)carbamate is its use as an intermediate in the synthesis of rofecoxib, a selective COX-2 inhibitor. The reliability of this intermediate directly impacts the scalability and cost-effectiveness of rofecoxib production. Procurement managers seeking to secure a stable supply of this critical component will find that partnering with reputable manufacturers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., offers significant advantages. They provide consistent quality, competitive pricing, and a commitment to meeting the demanding requirements of the pharmaceutical industry.

Beyond rofecoxib, this chemical intermediate serves as a valuable building block in broader organic synthesis. Researchers engaged in the development of novel compounds for various therapeutic areas can leverage its reactivity to construct intricate molecular architectures. The compound's stability under normal conditions and its solubility in common organic solvents like methanol and ethanol further enhance its utility in laboratory and industrial settings. This makes it an attractive choice for R&D scientists looking to optimize their synthetic processes.

When evaluating suppliers, it is essential to consider not just the price but also the quality assurance, manufacturing capabilities, and the supplier's track record. NINGBO INNO PHARMCHEM CO.,LTD. stands out as a trusted manufacturer and supplier, offering tert-Butyl N-(3-aminophenyl)carbamate with detailed specifications and excellent customer support. For those looking to buy this key pharmaceutical intermediate, understanding the supplier's commitment to quality and regulatory compliance is as important as the chemical's intrinsic properties. Engaging with a knowledgeable supplier can streamline your procurement process and ensure the successful development of your pharmaceutical products.