The Science Behind 2-Chloro-3-cyanopyridine: Properties and Synthesis
For R&D scientists and formulation chemists, a deep understanding of the chemical properties and synthesis pathways of key intermediates is crucial for successful product development. 2-Chloro-3-cyanopyridine (CAS 6602-54-6) is a compound that consistently garners attention due to its significant utility in various synthetic endeavors. As a dedicated manufacturer of fine chemicals and pharmaceutical intermediates, we aim to provide insights into why this particular molecule is so valuable.
Chemically known as 2-Chloro-3-cyanopyridine, this compound presents itself as a white to off-white crystalline powder. Its molecular formula, C6H3ClN2, and a molecular weight of approximately 138.55 g/mol, provide the fundamental basis for its reactivity. The presence of both a chlorine atom and a nitrile group on a pyridine ring imparts unique chemical characteristics, making it an attractive synthon for organic chemists. The typical purity level offered by reliable manufacturers, such as ourselves, often exceeds 99.00% by HPLC, ensuring minimal interference from impurities in complex synthesis reactions.
The melting point of 2-Chloro-3-cyanopyridine typically falls within the range of 104-109°C, indicating its solid state at room temperature and its relative stability. This characteristic is important for handling, storage, and precise dosing in chemical reactions. While various synthetic routes exist, common industrial production methods often involve the chlorination of related pyridine derivatives, such as 3-cyanopyridine N-oxide, using chlorinating agents like phosphorus oxychloride (POCl3). The optimization of these processes is key to achieving high yields and purity, which is a hallmark of our manufacturing capabilities.
The versatility of 2-Chloro-3-cyanopyridine stems from its dual functional groups. The chlorine atom can readily participate in nucleophilic substitution reactions, while the nitrile group can be hydrolyzed, reduced, or otherwise transformed into various other functional groups. This inherent reactivity allows for its application in the synthesis of a broad spectrum of complex molecules, including active pharmaceutical ingredients (APIs) and advanced agrochemicals. For researchers and procurement managers seeking to buy this compound, understanding these chemical nuances helps in planning synthesis strategies and selecting the right supplier.
As a prominent 2-Chloro-3-cyanopyridine manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. is committed to not only producing this intermediate but also ensuring its consistent quality and availability. Our advanced synthesis techniques and rigorous quality control protocols are designed to meet the exacting standards required by the pharmaceutical and agrochemical industries. By providing detailed technical data and reliable product specifications, we empower our clients to confidently utilize 2-Chloro-3-cyanopyridine in their innovative projects.
In summary, the chemical properties and well-established synthesis methods of 2-Chloro-3-cyanopyridine make it an indispensable tool in the chemist's arsenal. Its crystalline form, high purity, and reactive functional groups ensure its continued importance in driving advancements in both medicine and agriculture. For those seeking to purchase this critical intermediate, engaging with experienced suppliers who prioritize quality and technical expertise is paramount.
Perspectives & Insights
Data Seeker X
“While various synthetic routes exist, common industrial production methods often involve the chlorination of related pyridine derivatives, such as 3-cyanopyridine N-oxide, using chlorinating agents like phosphorus oxychloride (POCl3).”
Chem Reader AI
“The optimization of these processes is key to achieving high yields and purity, which is a hallmark of our manufacturing capabilities.”
Agile Vision 2025
“The versatility of 2-Chloro-3-cyanopyridine stems from its dual functional groups.”