2,2,2-Trifluoro-1-methoxyethanol, identified by CAS number 431-46-9, stands as a significant compound in the realm of specialized organic chemistry. This fluorinated molecule is characterized by its distinct structure, incorporating a trifluoromethyl group (CF3) and a methoxy group (-OCH3) attached to an ethanol backbone. Its designation as a methyl hemiacetal of trifluoroacetaldehyde underscores its chemical reactivity and utility as a synthetic precursor. With a molecular formula of C3H5F3O2 and a molecular weight of approximately 130.07 g/mol, it possesses unique properties that make it invaluable across various scientific and industrial applications.

From a physical standpoint, 2,2,2-Trifluoro-1-methoxyethanol is typically supplied as a clear, colorless liquid. Its key physicochemical properties include a density around 1.25 g/cm³, a boiling point in the range of 100-102°C, and a flash point of 42°C. These characteristics are crucial for chemists and process engineers when designing synthetic routes, ensuring safe handling, storage, and reaction conditions. The compound’s reactivity as a hemiacetal allows for controlled transformations, making it a preferred choice over its more volatile and reactive parent aldehyde, trifluoroacetaldehyde, especially in laboratory settings and industrial production where safety and precision are paramount.

The primary applications of 2,2,2-Trifluoro-1-methoxyethanol are rooted in its ability to serve as a versatile building block in organic synthesis. It is extensively used for introducing trifluoromethyl groups, which are known to impart desirable properties such as increased lipophilicity, enhanced metabolic stability, and altered electronic characteristics to molecules. This makes it particularly relevant in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and in the agrochemical sector for developing advanced crop protection agents. Furthermore, its role extends to material science, where fluorinated compounds often exhibit unique thermal, chemical, and mechanical properties.

For businesses seeking to procure this essential intermediate, identifying a reliable supplier of 2,2,2-Trifluoro-1-methoxyethanol is critical. Companies specializing in fluorochemicals, such as NINGBO INNO PHARMCHEM CO.,LTD., offer technical-grade products with comprehensive technical data and support. When considering where to buy 2,2,2-Trifluoro-1-methoxyethanol, it is advisable to look for manufacturers with a robust quality control system and a commitment to customer service. The ability to purchase 2,2,2-Trifluoro-1-methoxyethanol in bulk quantities from a trusted manufacturer in China can significantly streamline the procurement process for research institutions and chemical manufacturers alike, ensuring access to this vital component for their innovative projects.