The development of effective treatments for chemotherapy-induced nausea and vomiting (CINV) has revolutionized supportive care for cancer patients. Central to these advancements are compounds like Netupitant and Fosnetupitant, NK-1 receptor antagonists that significantly alleviate these distressing symptoms. The synthesis of these sophisticated drugs is made possible through the availability of high-quality chemical intermediates, among which N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide stands out. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of this crucial intermediate, understanding its pivotal role in anti-emetic drug synthesis.

N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide, identified by its CAS number 342417-04-3, serves as a critical building block in the multi-step chemical synthesis of Netupitant. This compound's specific molecular structure and high purity (assay ≥98.0%) are essential for ensuring the subsequent reaction steps proceed efficiently and yield the desired pharmaceutical product. Similarly, it is indispensable in the pathway leading to Fosnetupitant, a pro-drug form of Netupitant, further emphasizing its importance in the field of anti-emetic therapy. Our role as a Netupitant and Fosnetupitant intermediate manufacturer ensures that these vital drugs can be produced reliably.

For pharmaceutical companies engaged in drug development and manufacturing, sourcing reliable and high-purity intermediates is a non-negotiable aspect of their operations. NINGBO INNO PHARMCHEM CO.,LTD. provides this essential compound, packaged conveniently and stored under appropriate conditions to maintain its integrity. The consistent supply of white to off-white powder form of N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide supports uninterrupted production cycles, a critical factor in meeting market demands and patient needs. We are committed to being a leading supplier of this essential chemical intermediate.

By providing this key component, NINGBO INNO PHARMCHEM CO.,LTD. actively contributes to the therapeutic arsenal against CINV. Our expertise as a pharmaceutical intermediate supplier ensures that the quality and reliability of N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide meet the exacting standards of the pharmaceutical industry, reinforcing our commitment to advancing healthcare through chemical innovation.