The Technical Edge: Properties & Applications of 3,5-Dichloroaniline (CAS 626-43-7)
For chemists, engineers, and procurement specialists in the B2B chemical sector, a deep understanding of a compound's technical specifications is crucial for successful application and sourcing. 3,5-Dichloroaniline (CAS 626-43-7) is one such compound, whose precise properties make it a sought-after intermediate in various high-value industries. This article explores its key technical attributes and diverse applications, emphasizing why its sourcing demands meticulous attention.
3,5-Dichloroaniline, with the molecular formula C6H5Cl2N, is a substituted aniline derivative. Its physical properties are notable: it typically presents as a white to grey or dark grey crystalline solid. The melting point range, often cited between 46-52 °C, indicates its solid state under standard laboratory conditions. Its solubility profile is also important; it exhibits limited solubility in water (approximately 0.6 g/L at 26 °C) but is more soluble in organic solvents like ethanol and ether. This differential solubility is often exploited in purification and reaction processes. For procurement professionals, understanding these physical characteristics helps in handling, storage, and application planning.
The chemical reactivity of 3,5-Dichloroaniline stems from its aromatic amine functional group and the presence of two chlorine atoms on the benzene ring. This specific substitution pattern makes it a versatile synthon. It is frequently used as a starting material or intermediate in the synthesis of more complex molecules. For instance, its role in creating effective inhibitors of plant enzymes highlights its significance in the agrochemical sector. Researchers seeking to develop new crop protection agents often investigate '3,5-dichloroaniline for pesticide synthesis' to understand its potential.
The dye industry leverages 3,5-Dichloroaniline for its ability to form stable chromophores. By reacting it with other compounds, manufacturers can create a palette of colors with desired fastness properties. The precise positioning of the chlorine atoms influences the electronic properties of the resulting dye molecules, affecting their hue and stability. Dye formulators and manufacturers will look for 'supplier of 3,5-dichloroaniline for dye production' to ensure they are sourcing a reliable component for their colorants.
In the pharmaceutical realm, 3,5-Dichloroaniline serves as a critical intermediate in the synthesis of various active pharmaceutical ingredients (APIs). The chlorine substituents can be key structural elements in drugs designed to interact with specific biological targets. For example, it has been implicated in the synthesis of anti-tumor agents. Pharmaceutical R&D teams and manufacturing departments require extremely high purity, often specifying 99% or more. When searching for 'pharmaceutical intermediate CAS 626-43-7', buyers prioritize consistency and robust quality control from their chemical suppliers.
For those looking to purchase 3,5-Dichloroaniline, particularly from China, understanding the manufacturing process and quality control measures is essential. Manufacturers who provide detailed technical data sheets, including specifications for purity, melting point, and spectroscopic data (like IR and NMR), are preferred. Furthermore, competitive pricing for bulk quantities and reliable logistics are crucial considerations. For any chemical manufacturer or formulator, having a dependable source for this key intermediate is fundamental to their production success.
Perspectives & Insights
Alpha Spark Labs
“The melting point range, often cited between 46-52 °C, indicates its solid state under standard laboratory conditions.”
Future Pioneer 88
“Its solubility profile is also important; it exhibits limited solubility in water (approximately 0.”
Core Explorer Pro
“This differential solubility is often exploited in purification and reaction processes.”