In the realm of synthetic organic chemistry, certain molecules act as linchpins, enabling the construction of complex structures vital for various industries. 2,6-Difluorophenylacetic Acid (CAS: 85068-28-6) stands out as one such versatile intermediate. Its unique chemical structure, marked by two fluorine atoms in the ortho positions of a phenyl ring attached to an acetic acid group, grants it specific reactivity and properties that are highly valued. Understanding its applications and how to procure it effectively is key for researchers and manufacturers alike.

Understanding the Chemical Structure and Properties

The presence of fluorine atoms in organic molecules often leads to significant alterations in their physical and chemical properties. In the case of 2,6-Difluorophenylacetic Acid, these fluorine atoms exert a strong electron-withdrawing effect. This inductive effect impacts the acidity of the carboxylic acid group and influences the reactivity of the aromatic ring in subsequent reactions. Typically available with a purity of ≥98.0%, this compound is a reliable choice for demanding synthetic procedures. Its physical state is usually a white to off-white powder, with a melting point around 100-102 °C, making it relatively easy to handle and store.

Applications Across Industries

The versatility of 2,6-Difluorophenylacetic Acid is best illustrated by its diverse applications:

1. Pharmaceutical Intermediates: This is perhaps its most prominent application. The difluorophenylacetic acid moiety is a common structural feature in numerous biologically active compounds. As a key intermediate, it is used in the synthesis of pharmaceuticals targeting various therapeutic areas, including anti-inflammatory drugs, analgesics, and potentially novel antibiotics or antiviral agents. The ability to introduce this specific fluorinated phenylacetic acid structure efficiently is crucial for drug discovery and development. For pharmaceutical companies, sourcing this intermediate from a reliable manufacturer ensures consistent quality and compliance with regulatory standards. Enquiring about the price for bulk quantities is a standard practice for R&D departments.

2. Agrochemical Synthesis: In the agricultural sector, the development of potent yet environmentally conscious crop protection agents is a constant goal. 2,6-Difluorophenylacetic Acid serves as a valuable building block for synthesizing novel herbicides and pesticides. Its incorporation can lead to active ingredients with enhanced efficacy, improved selectivity, and potentially more favorable degradation profiles in the environment. Agricultural chemical companies rely on dependable suppliers to provide this intermediate, often seeking out partners who can offer technical support and consistent supply chains. Utilizing search terms like 'buy 2,6-difluorophenylacetic acid' or 'CAS 85068-28-6 for agrochemical use' can lead to such partnerships.

3. Material Science: The unique properties conferred by the fluorine atoms also make 2,6-Difluorophenylacetic Acid relevant in material science. It can be incorporated into the synthesis of specialized polymers or advanced functional materials. These materials might exhibit enhanced thermal stability, improved chemical resistance, or unique optical or electronic properties, making them suitable for high-performance applications in electronics, coatings, or aerospace. Researchers in material science often look for unique precursors to push the boundaries of material innovation.

4. General Organic Synthesis: Beyond these specific industries, 2,6-Difluorophenylacetic Acid is a valuable reagent in general organic chemistry research. It can be used in various coupling reactions, functional group transformations, and as a starting point for the synthesis of complex organic molecules in academic and industrial R&D settings. Its well-defined reactivity makes it a predictable component in multi-step synthesis pathways.

Procuring 2,6-Difluorophenylacetic Acid

When seeking to purchase 2,6-Difluorophenylacetic Acid, it is essential to identify suppliers who can guarantee its purity and provide comprehensive technical documentation. Manufacturers in regions like China have become significant sources for such fine chemical intermediates, offering competitive pricing and robust production capabilities. Prospective buyers should consider using search queries that include terms such as '2,6-difluorophenylacetic acid supplier China' or 'organic synthesis intermediate for sale' to identify potential partners. Direct communication with manufacturers can provide valuable insights into availability, lead times, and bulk discounts, facilitating the procurement process for any scale of project.

In summary, 2,6-Difluorophenylacetic Acid is a testament to the power of thoughtful molecular design. Its widespread application as an intermediate underscores its importance in driving innovation across pharmaceutical, agrochemical, and material science fields. By understanding its properties and strategic sourcing, chemists and manufacturers can leverage this versatile compound to create the next generation of advanced products.