In the intricate world of pharmaceutical manufacturing, the quality and precision of chemical intermediates are paramount. One such vital compound is (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone, readily available from NINGBO INNO PHARMCHEM CO.,LTD. This molecule, identified by its CAS number 149198-47-0, plays an indispensable role as a key intermediate in the synthesis of Cabazitaxel. Cabazitaxel is a potent semi-synthetic taxane derivative that has proven effective in treating metastatic prostate cancer, a significant advancement in oncology.

The significance of (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone lies in its meticulously engineered structure. This compound possesses specific stereochemical features, including a triethylsilyl-protected hydroxyl group and a Boc-protected nitrogen atom. These characteristics are crucial for imparting the correct three-dimensional configuration to the final Cabazitaxel molecule. The therapeutic efficacy of chemotherapy drugs like Cabazitaxel is highly dependent on their precise molecular architecture, making the purity and stereospecificity of intermediates like this non-negotiable. NINGBO INNO PHARMCHEM CO.,LTD. ensures that this intermediate is produced with an assay of ≥98.0%, meeting the stringent demands of the pharmaceutical industry.

The physical and chemical properties of (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone further highlight its utility. Described as a colorless to light yellow oily liquid, it exhibits characteristics such as a density of approximately 1.1 g/cm³, a high boiling point of around 463.1 °C at 760 mmHg, and a flash point of approximately 233.9 °C. These properties contribute to its stability during handling and storage, which is vital for large-scale pharmaceutical production. Proper storage in a cool, ventilated environment is recommended by NINGBO INNO PHARMCHEM CO.,LTD. to maintain its integrity.

As a leading pharmaceutical intermediate manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing reliable supply chains for critical drug components. The ability to source high-quality (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone from China empowers global pharmaceutical companies to maintain consistent production of life-saving treatments. For those seeking to buy (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone, partnering with experienced suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to both quality products and technical expertise. The synthesis of Cabazitaxel is a complex process, and having a dependable source for essential building blocks is key to success in the competitive pharmaceutical landscape.