In the realm of advanced organic synthesis, specific chemical reagents often become the linchpins of breakthrough discoveries and efficient production processes. Cyclopropylboronic Acid (CAS 411235-57-9) is one such compound, a versatile organoboronic acid that finds extensive utility across various sectors, most notably in pharmaceuticals and agrochemicals. Its unique structural motif—a cyclopropane ring attached to a boronic acid group—enables it to participate effectively in a range of cross-coupling reactions, making it a coveted building block for chemists worldwide.

Understanding where to buy this essential chemical and appreciating its diverse applications is key for any R&D scientist or procurement specialist. As a leading manufacturer and supplier of fine chemicals, we aim to shed light on the principal applications of Cyclopropylboronic Acid, highlighting why it's such a critical component in modern synthesis.

1. Pharmaceutical Intermediates and API Synthesis

This is arguably the most significant application for Cyclopropylboronic Acid. The cyclopropane ring is often incorporated into drug molecules to enhance their pharmacological properties, such as lipophilicity, metabolic stability, and receptor binding affinity. Cyclopropylboronic Acid serves as a crucial intermediate in the synthesis of numerous Active Pharmaceutical Ingredients (APIs). For example, it's employed in creating candidates for oncology, central nervous system disorders, and infectious diseases. When seeking to purchase these intermediates, ensuring high purity (often ≥98.0%) is paramount, as even trace impurities can affect the final drug's efficacy and safety. The price of this high-purity grade reflects its critical role in sensitive pharmaceutical manufacturing processes.

2. Suzuki-Miyaura Cross-Coupling Reactions

As previously mentioned, Cyclopropylboronic Acid is a prime substrate for Suzuki-Miyaura coupling. This palladium-catalyzed reaction is incredibly powerful for forming carbon-carbon bonds. It allows for the regioselective and stereoselective synthesis of complex organic molecules by coupling the cyclopropyl group with aryl or vinyl halides/triflates. This efficiency makes it a preferred reagent for building intricate molecular structures found in pharmaceuticals, natural products, and advanced materials. Researchers frequently search for a reliable supplier of Cyclopropylboronic Acid specifically for these coupling reactions.

3. Agrochemical Development

Beyond human pharmaceuticals, Cyclopropylboronic Acid also plays a role in the agrochemical industry. It acts as a key intermediate in the synthesis of various pesticides, herbicides, and fungicides. The incorporation of the cyclopropyl group can modify the bioactivity and environmental persistence of these agricultural chemicals, leading to more effective and potentially safer crop protection agents. The demand for innovative agrochemicals ensures a steady market for compounds like Cyclopropylboronic Acid.

4. Material Science and Specialty Chemicals

The unique electronic and structural properties conferred by the cyclopropane ring also make Cyclopropylboronic Acid valuable in certain material science applications. It can be used in the synthesis of functionalized polymers, advanced organic electronic materials, or as a component in novel catalysts. While not as widespread as its pharmaceutical applications, its potential in niche material development is continually being explored.

5. Research and Development Tool

For academic and industrial researchers, Cyclopropylboronic Acid is an essential tool for exploring new synthetic methodologies and creating novel chemical entities. Its predictable reactivity in various palladium-catalyzed reactions, along with other boronic acid transformations, allows chemists to design and execute complex synthetic routes efficiently. When starting new projects, sourcing a dependable manufacturer for reagents like this is a fundamental step.

Choosing the Right Supplier

When you are ready to buy Cyclopropylboronic Acid, selecting the right supplier is crucial. Factors to consider include product purity, consistency, available documentation (like COAs), pricing, and customer service. As a dedicated manufacturer and supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality Cyclopropylboronic Acid that meets the rigorous demands of these diverse applications. We understand that finding the right price and ensuring a stable supply chain are critical for your success.

Conclusion

Cyclopropylboronic Acid is far more than just a chemical reagent; it's an enabler of innovation across multiple industries. Its versatility in synthesis, particularly through Suzuki coupling, and its impact on the properties of derived molecules solidify its importance. Whether for pharmaceutical intermediates, agrochemicals, or advanced materials, ensuring a reliable source for this compound is key. Explore our offerings and discover how we can support your next breakthrough.