Trans-4-Aminocyclohexanol (CAS: 27489-62-9) is far more than just another chemical compound; it is a cornerstone intermediate in the synthesis of vital pharmaceuticals, most notably Ambroxol hydrochloride. Ambroxol hydrochloride is widely used as a mucolytic agent, aiding in the treatment of respiratory conditions characterized by excessive or viscous mucus. The precise structure and high purity of Trans-4-Aminocyclohexanol are therefore critical for the efficacy and safety of the final drug product. For any pharmaceutical company or contract manufacturer looking to buy this essential compound, understanding its significance and sourcing it from a reputable manufacturer is paramount.

The Chemical Profile of Trans-4-Aminocyclohexanol

As a white to light yellow crystalline powder, Trans-4-Aminocyclohexanol possesses a unique combination of an amino and hydroxyl group on a cyclohexane ring. This dual functionality makes it highly reactive and suitable for various synthetic pathways. Its physical properties, such as a melting point typically between 108-113°C and a density around 1.037 g/cm³, contribute to its handling and processing characteristics. The 'trans' configuration is crucial, influencing the stereochemistry of subsequent reactions, which is often vital in pharmaceutical synthesis to achieve the desired biological activity and avoid unwanted side effects.

Role in Ambroxol Hydrochloride Synthesis

The primary application driving the demand for Trans-4-Aminocyclohexanol is its role as a key intermediate in the production of Ambroxol hydrochloride. The synthesis typically involves reacting Trans-4-Aminocyclohexanol with specific reagents, often under controlled catalytic conditions. The reliability and purity of the Trans-4-Aminocyclohexanol directly influence the yield and quality of the final Ambroxol hydrochloride API. Therefore, sourcing this intermediate from a trusted supplier that guarantees high purity (≥99.0%) is essential for pharmaceutical manufacturers.

Beyond Ambroxol: Other Applications

While its role in Ambroxol synthesis is prominent, Trans-4-Aminocyclohexanol also finds utility in broader organic synthesis and chemical research. It serves as a valuable chiral building block for developing other complex molecules, including potential drug candidates in early-stage discovery programs. Its reactive functional groups allow it to participate in a wide array of chemical transformations, making it a versatile compound for chemists and researchers.

Sourcing from a Trusted Manufacturer

When seeking to procure Trans-4-Aminocyclohexanol, it is crucial to partner with a reliable manufacturer. Look for suppliers who provide detailed product specifications, verifiable quality control data, and consistent availability. Factors such as competitive Trans-4-Aminocyclohexanol price, responsive customer service, and efficient logistics are also important considerations. We, at NINGBO INNO PHARMCHEM CO.,LTD., are a dedicated supplier focused on delivering high-purity intermediates like Trans-4-Aminocyclohexanol, ensuring your production runs smoothly. Contact us today for a quote and learn more about how we can support your pharmaceutical manufacturing needs.