The pursuit of novel therapeutic strategies often leads researchers to explore the complex mechanisms of epigenetics. DNA methylation, a fundamental epigenetic modification, plays a critical role in gene regulation and is heavily implicated in the pathogenesis of numerous diseases, including cancer and myelodysplastic syndromes (MDS). Consequently, compounds that can modulate this process, such as DNA methyltransferase (DNMT) inhibitors, are of immense interest in pharmaceutical R&D.

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