In the complex landscape of pharmaceutical manufacturing, the selection of high-quality chemical intermediates is a cornerstone of successful drug development. Among these, fluorinated organic compounds, such as those derived from trifluoroacetophenone, play a critical role. This article examines the importance of 2,2,2-trifluoro-1-(3,4,5-trichlorophenyl)ethanone (CAS 158401-00-4) as a key pharmaceutical intermediate and provides insights for R&D scientists and procurement managers looking to buy this essential chemical.

Trifluoroacetophenone: A Versatile Building Block

Trifluoroacetophenone derivatives, characterized by the presence of both a trifluoromethyl group and a phenyl ketone structure, offer unique reactivity and properties valuable in organic synthesis. The specific compound, 2,2,2-trifluoro-1-(3,4,5-trichlorophenyl)ethanone, stands out due to its chlorinated phenyl ring and trifluoromethyl group, making it an excellent precursor for a variety of biologically active molecules. Its utility as a Lotilaner intermediate underscores its importance in the synthesis of veterinary pharmaceuticals, contributing to global animal health solutions.

For professionals in drug discovery and formulation, understanding the chemical properties and application scope of such intermediates is crucial. The ability to purchase these compounds from reputable manufacturers is key to ensuring the integrity of the research and production pipelines. When considering a purchase, always verify the purity and specifications, looking for assay values that meet stringent pharmaceutical standards, typically ≥99.0%.

Sourcing Strategies for Pharmaceutical Intermediates

Procuring pharmaceutical intermediates requires a strategic approach, focusing on reliability, quality, and cost-effectiveness. When seeking 2,2,2-trifluoro-1-(3,4,5-trichlorophenyl)ethanone, consider the following:

  1. Supplier Reputation: Partner with established manufacturers and suppliers with a proven history in providing pharmaceutical-grade chemicals. Companies based in China are often competitive sources for these intermediates.
  2. Quality Assurance: Ensure the supplier provides comprehensive documentation, including Certificates of Analysis (CoA), and adheres to international quality management standards.
  3. Pricing and Volume: Obtain quotes for different quantities, from R&D samples to bulk industrial supply. Understanding the price per kilogram can optimize your procurement budget.
  4. Technical Support: Choose suppliers who can offer technical assistance and are responsive to your queries, ensuring a smooth procurement process.

By adopting these sourcing strategies, you can confidently acquire the necessary trifluoroacetophenone intermediate for your pharmaceutical synthesis needs. This proactive approach ensures that your projects are supported by high-quality materials, paving the way for successful drug development and market introduction.

We encourage you to explore our offerings for high-purity 2,2,2-trifluoro-1-(3,4,5-trichlorophenyl)ethanone and discover how our reliable supply chain and commitment to quality can benefit your operations. Contact us today for a quote and to discuss your specific requirements.