The Importance of Trifluoromethyl and Fluorophenyl Groups in Organic Synthesis
In the realm of advanced organic synthesis, specific functional groups often dictate the properties and applications of a molecule. N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide (CAS 90356-78-8) exemplifies the strategic use of trifluoromethyl (-CF3) and fluorophenyl groups. These moieties impart unique characteristics to molecules, influencing their reactivity, lipophilicity, metabolic stability, and binding affinities. The trifluoromethyl group, known for its electron-withdrawing nature and steric bulk, can significantly alter a compound's electronic properties and enhance its stability. Similarly, the fluorophenyl group contributes to improved pharmacokinetic profiles and can engage in specific interactions within biological systems. These features are critical when the compound serves as a pharmaceutical intermediate, such as in the synthesis of Bicalutamide. As a dedicated manufacturer and supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. specializes in producing complex organic molecules that incorporate such valuable functional groups. We understand the intricate synthesis required to incorporate trifluoromethyl and fluorophenyl units reliably. By providing high-quality intermediates like CAS 90356-78-8, we empower researchers and manufacturers to leverage these advanced chemical features for innovative applications in pharmaceuticals, agrochemicals, and material science. Our commitment to quality ensures you receive intermediates with precisely engineered molecular structures.
Perspectives & Insights
Alpha Spark Labs
“In the realm of advanced organic synthesis, specific functional groups often dictate the properties and applications of a molecule.”
Future Pioneer 88
“N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide (CAS 90356-78-8) exemplifies the strategic use of trifluoromethyl (-CF3) and fluorophenyl groups.”
Core Explorer Pro
“These moieties impart unique characteristics to molecules, influencing their reactivity, lipophilicity, metabolic stability, and binding affinities.”