In the realm of ophthalmic pharmaceuticals, Trifluridine (CAS 70-00-8) stands out as a highly effective antiviral agent. For manufacturers and formulators seeking potent ingredients to combat viral ocular infections, understanding the properties and sourcing of Trifluridine is essential. NINGBO INNO PHARMCHEM CO.,LTD., a leading chemical manufacturer and supplier, provides critical insights into this compound.

What is Trifluridine and How Does it Work?

Trifluridine is a synthetic pyrimidine nucleoside analogue. Its primary medical application is as an ophthalmic solution to treat epithelial keratitis and keratoconjunctivitis caused by the herpes simplex virus (HSV). The drug's mechanism of action involves inhibiting viral DNA synthesis. By mimicking natural nucleosides, Trifluridine is incorporated into the growing viral DNA chain, but its trifluoromethyl group disrupts proper base pairing, leading to faulty DNA and preventing viral replication. This targeted action makes it a powerful tool against infections like herpes simplex keratitis.

Applications and Benefits in Ophthalmic Treatments

The primary use of Trifluridine is in the formulation of eye drops. Its efficacy against HSV types 1 and 2 has been well-established, making it a cornerstone treatment for recurrent ocular herpes infections. Beyond HSV, it also shows activity against vaccinia virus infections of the eye. The advantages of using Trifluridine as an active pharmaceutical ingredient include:

  • Targeted Antiviral Activity: Directly inhibits viral replication with minimal impact on host cells when used as directed.
  • Proven Clinical Efficacy: Demonstrates high success rates in healing herpetic corneal ulcers.
  • Established Safety Profile: When used as prescribed, it offers a good balance of efficacy and tolerability for ophthalmic use.

Procuring Trifluridine: A Supplier's Perspective

For pharmaceutical companies looking to buy Trifluridine, sourcing from a reliable manufacturer is critical. NINGBO INNO PHARMCHEM CO.,LTD. serves as a key supplier of this pharmaceutical intermediate. We ensure our Trifluridine (CAS 70-00-8) is produced under strict quality controls, meeting the high standards required for ophthalmic drug manufacturing. Our competitive pricing and consistent supply make us an ideal partner for businesses seeking to integrate Trifluridine into their product lines. We invite you to inquire about our Trifluridine price and request a sample to assess its quality for your pharmaceutical needs.

As the demand for effective antiviral treatments continues to grow, Trifluridine remains a vital component. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting the pharmaceutical industry with high-quality chemical intermediates like Trifluridine.