Microbiology laboratories worldwide rely on a variety of chemical agents to conduct essential research, diagnostics, and quality control. Trimethoprim Lactate Salt (CAS 23256-42-0) is one such compound that holds significant importance. Its specific mechanism of action—inhibiting bacterial dihydrofolate reductase—makes it a powerful tool for microbiologists. For labs looking to source this material, understanding its applications and identifying reliable suppliers is key.

One of the primary uses of Trimethoprim Lactate Salt in microbiology is in antimicrobial susceptibility testing (AST). This process is fundamental in clinical settings to determine which antibiotics will be most effective against a particular bacterial pathogen. Trimethoprim Lactate Salt is often incorporated into various AST formats, such as agar diffusion discs or broth microdilution panels, to test the sensitivity of bacterial isolates to this antibiotic. By observing the zones of inhibition or minimum inhibitory concentrations (MICs), scientists can guide antibiotic therapy, making the reliable availability of high-purity Trimethoprim Lactate Salt essential for accurate testing.

Furthermore, Trimethoprim Lactate Salt serves as a selective agent in culture media. In many research scenarios, it’s necessary to isolate specific types of bacteria while preventing the growth of others. By supplementing growth media with Trimethoprim Lactate Salt, researchers can create an environment where only bacteria that are either resistant to or not inhibited by trimethoprim can thrive. This is particularly useful in genetic studies, strain differentiation, and research involving bacteria that naturally possess resistance mechanisms.

For academic institutions and private research laboratories, sourcing Trimethoprim Lactate Salt requires careful consideration. It’s vital to buy from suppliers who can guarantee a high level of purity (e.g., ≥98%) and provide comprehensive technical documentation like Certificates of Analysis (CoA) and Safety Data Sheets (SDS). When searching for a manufacturer or supplier, look for companies with a proven track record in providing research-grade chemicals. Companies based in regions like China are often capable of offering competitive pricing, especially for bulk orders that might be needed for extensive research projects.

Researchers and lab managers should prioritize suppliers who offer timely delivery and responsive customer service, as these factors are crucial for uninterrupted research workflows. Whether for standard susceptibility testing or more specialized selection protocols, a consistent supply of quality Trimethoprim Lactate Salt is a cornerstone of successful microbiological research.