Understanding 1,2-Dimethoxybenzene (Veratrole): Chemical Properties and Applications
1,2-Dimethoxybenzene, commonly known by its synonym veratrole, is a foundational chemical compound with significant utility across multiple industrial sectors, most notably pharmaceuticals and fragrances. Possessing the CAS number 91-16-7 and the molecular formula C8H10O2, this aromatic ether is a colorless liquid that chemists and formulators find invaluable. Understanding its core chemical properties is the first step for any professional looking to leverage its potential in their specific applications.
The physical appearance of veratrole is a key identifier – a clear, colorless liquid. Its molecular weight is approximately 138.16 g/mol. These characteristics, combined with its boiling point of around 206-207 °C and a melting point of 15 °C, dictate its handling and storage requirements. As a chemical intermediate, its structure allows for participation in a variety of organic reactions, making it a versatile building block.
The primary application driving demand for 1,2-Dimethoxybenzene is its role as a pharmaceutical intermediate. It is instrumental in the synthesis pathways of numerous active pharmaceutical ingredients (APIs). The efficiency and purity of veratrole directly impact the quality and yield of these life-saving drugs. Furthermore, its fragrant nature makes it a sought-after ingredient in the creation of perfumes, cosmetics, and other scented products, adding to its commercial value.
For businesses that require this chemical, sourcing from reliable manufacturers is essential. Companies specializing in fine chemicals and intermediates, particularly those operating in China, often provide high-purity grades of veratrole, meeting stringent quality standards required by the pharmaceutical industry. When procuring, it is important to request detailed specifications, including purity assays (e.g., 99%min), and any relevant certifications.
Exploring the applications of 1,2-Dimethoxybenzene further reveals its importance. In chemical synthesis, it can undergo acylation reactions to yield derivatives like 3,4-dimethoxyacetophenone, which are themselves precursors for insecticides and medicinal compounds. This broad utility underscores why veratrole remains a staple in many chemical laboratories and manufacturing facilities. If you are looking to buy this chemical, ensuring a stable supply from a reputable manufacturer is key to maintaining your production flow and product quality.
Perspectives & Insights
Molecule Vision 7
“For businesses that require this chemical, sourcing from reliable manufacturers is essential.”
Alpha Origin 24
“Companies specializing in fine chemicals and intermediates, particularly those operating in China, often provide high-purity grades of veratrole, meeting stringent quality standards required by the pharmaceutical industry.”
Future Analyst X
“When procuring, it is important to request detailed specifications, including purity assays (e.”