For professionals in the chemical industry, a thorough understanding of key intermediates is crucial for successful product development and manufacturing. 1,6-Dibromohexane (CAS: 629-03-8) is one such vital compound, widely utilized across various sectors. This article provides a detailed look at its properties, synthesis, and applications, offering insights for B2B buyers seeking to procure this essential chemical.

What is 1,6-Dibromohexane?
1,6-Dibromohexane is a bifunctional organobromine compound with the chemical formula C6H12Br2. It is characterized by a six-carbon aliphatic chain with bromine atoms attached to the terminal carbons (positions 1 and 6). This structure imparts specific reactivity, making it an excellent alkylating agent and a versatile building block in organic synthesis.

Key Physical and Chemical Properties
Understanding the properties of 1,6-Dibromohexane is essential for its effective use:

  • Appearance: Typically a colorless to pale yellow transparent liquid.
  • Molecular Formula: C6H12Br2
  • Molecular Weight: Approximately 243.97 g/mol
  • CAS Number: 629-03-8
  • Density: Around 1.586 g/mL at 25 °C.
  • Melting Point: -2 °C
  • Boiling Point: 243 °C
  • Flash Point: 110 °C
  • Solubility: Insoluble in water, but soluble in many organic solvents like ethanol, ether, and chloroform.
  • Purity: High purity grades, often ≥99.0% by GC, are commonly available and required for precise chemical reactions.

Synthesis Methods
The primary method for synthesizing 1,6-Dibromohexane involves the bromination of 1,6-hexanediol. This is typically achieved by reacting the diol with hydrobromic acid (HBr) or using alternative brominating agents like phosphorus tribromide (PBr₃). The hydroxyl groups are substituted by bromine atoms, yielding the desired dibromoalkane. Purification is usually performed through fractional distillation to achieve the high purity levels required for commercial use.

Applications in Industry
1,6-Dibromohexane's utility spans several critical industries:

  • Organic Synthesis: It serves as a key intermediate for synthesizing a wide range of organic molecules, including active pharmaceutical ingredients (APIs) and agrochemicals. Its ability to introduce a C6 linker is invaluable.
  • Pharmaceuticals: Used in the development of drugs, notably as a precursor for hypotensive agents and compounds with potential antitumor activity.
  • Polymer Chemistry: Acts as a cross-linking agent for polymers and a monomer in the creation of advanced materials like ionomers for fuel cells and conductive polymers.
  • Materials Science: Employed in creating molecular architectures, sensors, and other specialized materials where precise spacing is required.

Sourcing Considerations for B2B Buyers
When looking to buy 1,6-Dibromohexane, it is essential to partner with a reputable manufacturer or supplier. Factors to consider include: guaranteed high purity (≥99.0%), consistent batch quality, competitive pricing, and reliable delivery. Sourcing from established manufacturers in China can offer significant advantages in terms of cost-effectiveness and availability for bulk orders. Always request Certificates of Analysis (CoA) to verify product specifications and ensure compliance with your application's requirements.

By understanding the fundamental aspects of 1,6-Dibromohexane, businesses can make informed purchasing decisions and leverage this versatile intermediate to drive their innovative projects forward.