The pharmaceutical industry constantly seeks reliable and high-quality chemical intermediates to fuel its innovation pipeline. Among these, halogenated aromatic compounds play a significant role, and 1-Iodonaphthalene (CAS: 90-14-2) stands out as a vital component in many synthetic routes. For R&D scientists and procurement professionals, understanding this compound's characteristics and sourcing channels is crucial for efficient drug discovery and development.

The Chemical Profile of 1-Iodonaphthalene

1-Iodonaphthalene is a derivative of naphthalene where an iodine atom is substituted at the alpha (1) position. Its molecular formula is C10H7I, and it has a molecular weight of approximately 254.07 g/mol. Physically, it is typically described as a light yellow liquid, with a melting point of 4°C and a boiling point of around 302°C at atmospheric pressure. The purity of 1-Iodonaphthalene is a critical parameter, with most industrial applications requiring a minimum of 97% purity. This high purity is essential to avoid unwanted side reactions and to ensure the quality of the final pharmaceutical product.

Critical Role in Pharmaceutical Development

The significance of 1-Iodonaphthalene in the pharmaceutical sector stems from its versatility as a synthetic intermediate. It acts as a precursor or building block in the synthesis of various complex organic molecules, which can eventually become Active Pharmaceutical Ingredients (APIs). Its iodine atom makes it amenable to a range of coupling reactions, such as Suzuki, Sonogashira, and Heck reactions, which are fundamental in modern organic chemistry and drug design. Researchers leverage these reactions to:

  • Synthesize novel therapeutic agents.
  • Develop more efficient routes to existing drugs.
  • Create specialized chemical libraries for high-throughput screening.

For pharmaceutical manufacturers, securing a consistent supply of high-purity 1-iodonaphthalene is non-negotiable. Fluctuations in quality or availability can lead to significant delays and increased costs in drug development cycles. Therefore, identifying a reputable 1-iodonaphthalene manufacturer with robust quality control measures is a strategic priority.

Sourcing Strategies and Market Insights

When seeking to buy 1-iodonaphthalene, particularly for research or production, exploring the market for a reliable 1-iodonaphthalene supplier in China is often a productive avenue. Chinese chemical manufacturers have become global leaders in producing a wide array of intermediates, offering competitive pricing for essential compounds like 1-iodonaphthalene. Companies looking for the best CAS 90-14-2 price can benefit from thorough market research and obtaining multiple quotes. It is advisable to work with suppliers who provide comprehensive documentation, including Certificates of Analysis (CoA), to verify the purity and specifications of the product.

At Ningbo Inno Pharmchem, we specialize in providing high-quality pharmaceutical intermediates, including 1-Iodonaphthalene. Our commitment to stringent quality standards and efficient production processes ensures that our clients receive reliable materials essential for their drug discovery and development efforts. We aim to be your preferred partner for sourcing critical chemical intermediates, offering competitive pricing and dependable service.