In the complex world of chemical manufacturing, intermediates are the unsung heroes that enable the creation of vital products. 1-Methylazepan-4-one Hydrochloride (CAS No. 19869-42-2) is one such compound, indispensable for the synthesis of Azelastine Hydrochloride, a widely used pharmaceutical. For procurement specialists and R&D scientists, understanding the detailed specifications and effective sourcing strategies for this intermediate is crucial for successful operations.

The chemical identity of 1-Methylazepan-4-one Hydrochloride is clearly defined by its CAS number, molecular formula (C7H14ClNO), and molecular weight (163.645). Its typical physical form as a yellow-brown powder, along with a melting point of 115-120°C, provides initial identification points. However, the critical factors that dictate its suitability for pharmaceutical applications lie in its purity and impurity profile. A high assay of ≥95.0% is standard, ensuring a significant concentration of the desired compound. Equally important are the stringent control limits for impurities: single impurities are typically kept below 1.5%, and total impurities do not exceed 5.0%. These parameters are vital for ensuring the quality and safety of the final Azelastine Hydrochloride product.

When looking to purchase 1-Methylazepan-4-one Hydrochloride, potential buyers should prioritize partnering with reputable manufacturers and suppliers. These entities are capable of providing consistent quality across batches, which is non-negotiable in pharmaceutical production. A thorough vetting process should include reviewing Certificates of Analysis (CoA) for each lot, which detail the specific purity and impurity levels. Additionally, inquiring about packaging options, such as the common 25 kg drums, and appropriate storage conditions will help ensure product integrity from receipt to use.

The competitive landscape for chemical intermediates means that buyers can often find attractive prices, especially when considering bulk orders. However, the decision to buy should be based on a balance of cost, quality, and reliability. Suppliers based in regions like China are often key players in the global market, offering extensive manufacturing capabilities. It is important to establish clear communication channels with these suppliers to discuss specific needs, potential lead times, and any necessary regulatory support. For instance, understanding the material's role as an intermediate for Azelastine Hydrochloride synthesis helps in framing precise inquiries.

In conclusion, the successful procurement of 1-Methylazepan-4-one Hydrochloride relies on a deep understanding of its specifications and a strategic approach to sourcing. By focusing on quality, reliability, and competitive pricing from trusted manufacturers and suppliers, pharmaceutical companies can ensure they have access to this essential intermediate, thereby supporting the consistent production of Azelastine Hydrochloride and contributing to public health.