For researchers in molecular biology and pharmacology, understanding the precise mechanisms of cellular signaling is key to unlocking new therapeutic strategies. Kinases, enzymes that play critical roles in these pathways, are often targets for drug development. 1-NM-PP1 (CAS 221244-14-0) has emerged as a highly valuable tool in this field, functioning as a potent and selective inhibitor of specific kinase variants. As a manufacturer and supplier of advanced biochemicals, we are committed to providing researchers with the high-quality compounds needed to advance their scientific exploration.

1-NM-PP1 is characterized by its cell-permeable nature and its ability to act as an ATP-competitive inhibitor. What sets it apart is its remarkable selectivity for mutant kinases over their wild-type counterparts. This means that when a kinase has undergone a specific mutation, 1-NM-PP1 can effectively inhibit its activity at much lower concentrations than it would affect the normal, wild-type enzyme. This specificity is crucial for experiments designed to isolate the effects of particular kinase mutations, which are often implicated in various diseases, including cancer and neurological disorders. The compound's physical form is typically a white solid, indicating its purity and suitability for sensitive biochemical assays.

The scientific community widely utilizes 1-NM-PP1 for a variety of research purposes. It is frequently employed in studies aimed at understanding the functional consequences of specific kinase mutations in cellular processes such as cell proliferation, apoptosis, and signal transduction. Researchers can purchase 1-NM-PP1 to investigate signaling pathways, validate kinase targets for drug development, and explore the efficacy of targeted therapies. For those looking to buy 1-NM-PP1, partnering with a reputable manufacturer ensures access to a product with guaranteed high purity, typically greater than 95% by HPLC, which is essential for obtaining reliable and reproducible results. We are a leading supplier in China, dedicated to this standard.

The versatility of 1-NM-PP1 extends to its use in both in vitro and in vivo studies. Its cell-permeable property allows for direct application in cell-based assays, while its inhibitory characteristics can be leveraged in animal models to understand the physiological roles of specific kinases. For researchers in academic institutions and pharmaceutical companies, securing a consistent and high-quality supply of this compound is vital. NINGBO INNO PHARMCHEM offers 1-NM-PP1, ensuring that scientists can confidently integrate it into their experimental designs. We are a trusted manufacturer providing this essential research tool.

In conclusion, 1-NM-PP1 (CAS 221244-14-0) is more than just a chemical compound; it is a precision instrument for scientific discovery. Its ability to selectively inhibit mutant kinases makes it an indispensable tool for understanding complex biological systems and for the development of targeted therapeutic agents. We encourage researchers and procurement specialists to consider NINGBO INNO PHARMCHEM as their primary supplier for 1-NM-PP1. Contact us today to request a quote and discover how our commitment to quality and service can support your scientific breakthroughs.