For professionals in the chemical and pharmaceutical industries, having a thorough understanding of key intermediates is vital for efficient procurement and successful application. 2,4-Difluorophenylacetic Acid (CAS: 81228-09-3) is a compound that consistently appears in synthetic routes for advanced pharmaceuticals and agrochemicals. This article aims to provide a clear overview of its properties, specifications, and the importance of sourcing from reputable suppliers.

Key Properties and Specifications
2,4-Difluorophenylacetic Acid is characterized by its molecular formula C8H6F2O2 and a molecular weight of 172.13 g/mol. It typically presents as a white powder, with a melting point range commonly cited between 115-118 °C. The CAS Number, 81228-09-3, serves as its unique identifier in chemical databases and regulatory filings. High purity is a critical specification, with most industrial applications requiring a minimum purity of 98%. This purity level is essential for ensuring predictable reaction outcomes and the quality of downstream products.

Significance in Synthesis
The presence of two fluorine atoms on the phenyl ring of 2,4-Difluorophenylacetic Acid significantly influences its chemical behavior. Fluorine substitution can enhance lipophilicity, alter electronic properties, and improve metabolic stability in biologically active molecules. These attributes make it an indispensable building block for:

  • Pharmaceutical Intermediates: Used in the synthesis of drugs targeting various therapeutic areas.
  • Agrochemicals: Incorporated into herbicides and other crop protection agents for improved efficacy and selectivity.
  • Organic Synthesis: A valuable reagent in academic and industrial research for creating complex organic structures.

Choosing a Reliable Supplier
When it comes to purchasing 2,4-Difluorophenylacetic Acid, selecting a reliable supplier is crucial. Factors to consider include:

  • Manufacturer vs. Distributor: Direct manufacturers often offer better pricing and more direct quality control.
  • Quality Documentation: Always request a Certificate of Analysis (CoA) to verify purity and specifications.
  • Supply Chain Stability: Ensure the supplier has a consistent production capacity and a track record of on-time deliveries.
  • Customer Support: Responsive communication and technical assistance are vital for smooth transactions.

NINGBO INNO PHARMCHEM CO.,LTD. as Your Go-To Supplier
NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier specializing in high-quality fine chemicals, including 2,4-Difluorophenylacetic Acid (CAS: 81228-09-3). We are committed to providing our clients with products that meet rigorous purity standards and are backed by reliable service. As a trusted China-based supplier, we understand the importance of consistent quality and competitive pricing for your production needs. We invite you to buy 2,4-Difluorophenylacetic Acid from us, assured of our dedication to excellence and customer satisfaction. Contact NINGBO INNO PHARMCHEM CO.,LTD. to learn more and fulfill your chemical sourcing requirements.