For chemists and material scientists engaged in advanced synthesis, understanding the specific properties of key intermediates is fundamental. 2,5-Dibromo-3-formylthiophene, a thiophene derivative identified by CAS number 1193-69-7, is one such critical compound. Its unique chemical structure, featuring two bromine atoms at the 2 and 5 positions and an aldehyde group at the 3 position of the thiophene ring, makes it an exceptionally versatile building block in organic synthesis.

The reactivity of 2,5-Dibromo-3-formylthiophene is a direct consequence of its molecular design. The aldehyde group is amenable to a wide array of nucleophilic addition reactions, Wittig reactions, and reductive aminations, allowing for the extension of carbon chains and the introduction of diverse functional groups. Simultaneously, the bromine atoms serve as excellent leaving groups in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura coupling, Stille coupling, and Sonogashira coupling. These reactions are cornerstones of modern synthetic organic chemistry, enabling the efficient construction of complex conjugated systems, polymers, and novel molecular architectures.

These versatile reaction pathways make 2,5-Dibromo-3-formylthiophene a sought-after intermediate in several high-tech industries. In organic electronics, it is used to synthesize conjugated polymers and small molecules for applications in OLEDs, OPVs, and organic field-effect transistors (OFETs). The ability to precisely control the electronic band gap and morphology of these materials through strategic functionalization makes this thiophene derivative invaluable. Furthermore, in the pharmaceutical sector, it acts as a key intermediate for the synthesis of various drug candidates and APIs, where its heterocyclic structure can impart specific biological activities.

When R&D scientists and purchasing managers look to buy 2,5-Dibromo-3-formylthiophene, they often seek suppliers who can guarantee high purity and reliable batch-to-batch consistency. Manufacturers in China are prominent suppliers, offering this intermediate with high purity levels, typically above 97%. It is advisable for potential buyers to consult detailed product specifications, request Certificates of Analysis (CoA), and consider ordering small sample quantities for initial validation. Understanding the molecular weight (269.94 g/mol) and molecular formula (C5H2Br2OS) is also essential for accurate stoichiometric calculations in synthesis planning.

The continued innovation in materials science and drug discovery ensures a sustained demand for sophisticated chemical intermediates. For those needing to purchase 2,5-Dibromo-3-formylthiophene, partnering with a well-established chemical manufacturer that prioritizes quality and technical support is the most effective strategy for ensuring project success and a stable supply chain.