For chemical industry professionals, a deep understanding of key intermediates is essential for efficient operations and innovation. 2-Bromo-5-chlorobenzonitrile, identified by its CAS number 57381-37-0, is one such compound that warrants close examination. This article delves into its chemical properties and provides insights into what to look for when dealing with manufacturers and suppliers of this critical intermediate.

Chemically, 2-Bromo-5-chlorobenzonitrile is characterized by its molecular formula C7H3BrClN and a molecular weight of 216.46. Its physical form is typically an off-white crystalline powder, with a melting point generally reported between 138.8-139.2°C. These properties are crucial for identification and handling. The compound's structure, featuring a benzonitrile ring with bromine and chlorine substituents, makes it highly valuable in organic synthesis, particularly for reactions requiring regioselective functionalization. The presence of both halogens offers distinct reactivity profiles, enabling its use in various cross-coupling reactions and other synthetic transformations.

When considering where to buy 2-Bromo-5-chlorobenzonitrile, it is imperative to engage with reliable manufacturers and suppliers. These partners should be able to provide comprehensive documentation, including Certificates of Analysis (COA), which detail purity levels (commonly 97% or higher) and confirm identity through techniques like NMR spectroscopy. Reputable companies, many of which are based in China, pride themselves on maintaining stringent quality control measures throughout their production processes.

The pricing for 2-Bromo-5-chlorobenzonitrile is influenced by several factors, including purity, order quantity, and market demand. As a widely used intermediate, it is often available from multiple sources, allowing buyers to compare offerings. Securing a stable supply at a competitive price is a key objective for procurement managers. Engaging with suppliers who offer bulk discounts and consistent availability can significantly reduce operational costs.

Furthermore, understanding the synthesis routes for 2-Bromo-5-chlorobenzonitrile can provide valuable insights into its potential impurities and the overall reliability of its production. Manufacturers often disclose general synthesis strategies, which can help in assessing their expertise and the robustness of their manufacturing processes. This information is invaluable when you need to purchase this chemical for demanding applications.

In essence, 2-Bromo-5-chlorobenzonitrile is a fundamental intermediate with broad applications. By carefully selecting manufacturers and suppliers, verifying product quality, and negotiating favorable pricing, organizations can ensure a secure and cost-effective supply of this essential chemical, thereby supporting their research and production objectives effectively.