2-Bromobenzoic Acid, identified by its CAS number 88-65-3, is a fundamental organic compound that serves as a critical intermediate in various chemical syntheses. Its unique structural features, including a bromine atom strategically positioned on the benzoic acid ring, make it highly versatile. As a key player in the chemical intermediate market, understanding its properties and applications is vital for researchers, formulators, and procurement specialists. We, as a dedicated manufacturer, aim to provide clarity on this important compound.

Physically, 2-Bromobenzoic Acid typically presents as a white to light yellow or beige crystalline powder. Its purity is a significant factor, with standard specifications often demanding a minimum of 97%. It exhibits good solubility in common organic solvents like ethanol and ether, though its solubility in water is limited, being more soluble in hot water. Key physical parameters such as its melting point (around 147-150°C) and boiling point (approximately 296°C at atmospheric pressure) are important for handling and processing.

Chemically, the bromine atom on the aromatic ring and the carboxylic acid group provide reactive sites that enable a wide array of transformations. The bromine can participate in nucleophilic substitution reactions and is particularly useful in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira couplings), allowing for the formation of new carbon-carbon bonds. The carboxylic acid group can be converted into esters, amides, acid halides, and can also undergo decarboxylation under specific conditions. This inherent reactivity is what makes it a valuable precursor in complex organic synthesis.

While specific synthesis routes can vary, 2-Bromobenzoic Acid is often prepared through the bromination of benzoic acid derivatives or through reactions involving aniline derivatives. The optimization of synthesis for industrial scale involves balancing yield, purity, cost, and environmental impact. As a leading supplier, our manufacturing processes are designed to consistently deliver high-quality product that meets these demanding criteria.

The applications of 2-Bromobenzoic Acid are broad and impactful. In the pharmaceutical industry, it is a crucial intermediate for synthesizing various APIs, including antifungal agents, antipsychotics, and anti-inflammatory drugs. Its use in creating complex drug molecules highlights its importance. For those looking to purchase this compound, seeking a reliable 2-bromobenzoic acid manufacturer in China ensures competitive pricing and consistent supply for your critical projects.

Furthermore, its role extends to the agrochemical sector, where it serves as a precursor for insecticides and fungicides, contributing to global food security. In the realm of fine chemicals, it finds use in the synthesis of dyes, pigments, and other specialty materials. Researchers also utilize it as a standard reagent for analytical measurements and as a versatile building block for novel compound discovery. Whether you are looking for a chemical raw material or a specific pharmaceutical intermediate, understanding the multifaceted nature of 2-Bromobenzoic Acid is key.