In the intricate world of pharmaceutical manufacturing, the selection and understanding of chemical intermediates are critical for success. 2-Bromobiphenyl (CAS 2052-07-5) stands out as a crucial building block, facilitating the synthesis of a wide array of active pharmaceutical ingredients (APIs) and other complex organic molecules. As a dedicated manufacturer and supplier, understanding the detailed properties of this compound is key to its effective utilization. This article delves into the essential physical and chemical characteristics of 2-Bromobiphenyl, highlighting why it is a preferred choice for pharmaceutical applications and where you can buy it from a reliable source.

Physical Appearance and State

A primary characteristic that defines 2-Bromobiphenyl is its appearance. It is consistently described as a colorless liquid. This liquid state at room temperature (with a melting point of approximately 1.5-2 °C) makes it convenient for handling, measuring, and incorporating into reaction mixtures without the need for initial dissolution, unlike solid intermediates. This ease of handling contributes to its appeal in laboratory research and large-scale manufacturing environments. As a trusted supplier in China, we ensure that our 2-Bromobiphenyl consistently meets this visual specification.

Key Chemical and Physical Properties

Beyond its appearance, several key properties make 2-Bromobiphenyl indispensable for synthetic chemists. Its molecular formula is C12H9Br, with a molecular weight of 233.11 g/mol. The boiling point is notably high, around 297-298 °C, indicating its thermal stability under many reaction conditions. The density is approximately 1.352 g/mL at 25 °C. Solubility information indicates it is slightly soluble in chloroform (when heated) and methanol, common organic solvents used in synthesis. These properties are crucial for chemists when designing reaction parameters, purification methods, and ensuring compatibility with other reagents.

Applications in Pharmaceutical Synthesis

The primary utility of 2-Bromobiphenyl lies in its role as a pharmaceutical intermediate. The bromine atom on the biphenyl structure provides a reactive site for various coupling reactions, such as Suzuki, Stille, or Buchwald-Hartwig couplings. These reactions are fundamental in constructing complex molecular architectures that form the basis of many modern drugs. For instance, it can be used in the synthesis of compounds with potential applications in areas like OLED technology and novel polymer development, showcasing its versatility beyond traditional pharmaceutical pathways. As a premier manufacturer, we are committed to supplying this compound at competitive prices to facilitate these advancements.

Sourcing High-Quality 2-Bromobiphenyl

When you need to buy 2-Bromobiphenyl, partnering with a reputable supplier is essential. We pride ourselves on being a leading manufacturer in China, offering high-purity 2-Bromobiphenyl (CAS 2052-07-5) that meets the exacting standards of the pharmaceutical industry. Our commitment to quality assurance and customer service ensures that you receive a product that is not only specification-compliant but also competitively priced, with a reliable supply chain to support your ongoing projects.

Understanding the physical and chemical properties of 2-Bromobiphenyl is the first step towards unlocking its full potential in your research and manufacturing processes. We encourage you to reach out to us to learn more about this vital intermediate and to secure a dependable supply from a trusted supplier.