For chemists and researchers navigating the vast landscape of organic synthesis, understanding the specific properties and potential applications of chemical intermediates is key to innovation. 2-Chloro-4-iodo-3-methylpyridine (CAS 153034-88-9) is a compound that warrants attention due to its unique structural characteristics and versatility. As a specialized pyridine derivative, it plays a significant role in the development of complex molecules.

Let's explore the fundamental properties of 2-Chloro-4-iodo-3-methylpyridine. Typically appearing as a white to light yellow or light orange powder to crystal, its physical state is indicative of its purity and handling requirements. The reported melting point range of 101-106°C suggests it is a stable solid under ambient conditions, facilitating storage and transportation. With a molecular weight of approximately 253.47 g/mol and a molecular formula of C6H5ClIN, this compound offers a precise molecular structure for chemists to manipulate.

The chemical reactivity of 2-Chloro-4-iodo-3-methylpyridine stems from the presence of both a chlorine atom and an iodine atom on the pyridine ring, alongside a methyl group. These functional groups provide multiple sites for regioselective reactions. The iodine atom, being a good leaving group, is particularly useful in cross-coupling reactions, such as Suzuki, Sonogashira, or Stille couplings, which are fundamental tools in modern organic synthesis for forming carbon-carbon bonds. The chlorine atom can also participate in various nucleophilic substitution or coupling reactions.

These reactive sites make 2-Chloro-4-iodo-3-methylpyridine an invaluable building block in several areas, most notably in the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs). Its pyridine core is a common motif in many biologically active molecules, and the strategic placement of halogen atoms allows for the precise introduction of diverse side chains and functional groups required for drug efficacy and targeting. Researchers often seek to buy this compound for custom synthesis projects aimed at discovering new therapeutic agents.

When sourcing this specialized chemical, reliability and purity are non-negotiable. As a trusted manufacturer and supplier of 2-Chloro-4-iodo-3-methylpyridine in China, we ensure that our product meets high standards of purity. We provide detailed specifications and are ready to offer samples and competitive prices for your research and development needs. Whether you are exploring new synthetic routes or scaling up existing processes, understanding the chemical behavior of this compound is key to success. Please contact us to learn more about how our high-quality chemical products can benefit your work.