For professionals in the chemical industry, a thorough understanding of key intermediates is crucial for innovation and efficient production. 2-Chloroethylamine hydrochloride (CAS 870-24-6) is one such indispensable compound, vital across pharmaceuticals, agrochemicals, dyes, and surfactants. As a leading manufacturer and supplier from China, we aim to provide comprehensive insights into its properties, synthesis, and applications, empowering your procurement and R&D decisions.

Chemical Identity and Properties:
2-Chloroethylamine hydrochloride, with the molecular formula C2H7Cl2N and CAS number 870-24-6, typically presents as a white to light beige crystalline powder. It exhibits a melting point range of 140-150 °C and has a pH value of 2-3 in aqueous solution. Its solubility in water is notable, with a solubility of 5666g/l, making it amenable to various aqueous-based synthesis processes. It is classified as hygroscopic, necessitating proper storage in a cool, dry place and tightly sealed containers to maintain its integrity and purity (typically ≥98.0% assay).

Synthesis Pathways:
The synthesis of 2-Chloroethylamine hydrochloride commonly involves the reaction of monoethanolamine hydrochloride with thionyl chloride in a solvent like benzene. This process, often carried out under controlled temperature conditions, yields the desired product with good purity. For instance, a typical synthesis involves heating monoethanolamine hydrochloride with dimethylformamide and benzene, followed by slow addition of thionyl chloride. The subsequent aqueous workup and extraction isolate the 2-chloroethylamine hydrochloride. As a manufacturer, optimizing these synthesis routes is key to achieving high yields and cost-effectiveness, ensuring we can offer competitive pricing to our B2B clients.

Key Applications and Uses:
The versatility of 2-Chloroethylamine hydrochloride stems from its reactive functional groups, making it a cornerstone intermediate in various sectors:

  • Pharmaceuticals: It is a critical intermediate for synthesizing Active Pharmaceutical Ingredients (APIs) like fluvoxamine maleate (an antidepressant) and certain anti-neoplastic agents used in cancer treatment.
  • Agrochemicals: It serves as a building block for producing pesticides and herbicides, contributing to crop protection and agricultural productivity.
  • Dyes and Surfactants: It is employed in the synthesis of specialized dyes, enhancing color properties and fastness, and in creating functional surfactants for detergents, emulsifiers, and personal care products.
  • Organic Synthesis: Beyond specific industry applications, it acts as a valuable reagent in general organic synthesis and as a derivatization reagent for amino acids, dipeptides, and nucleotides, which is important for research and analysis.

As a leading chemical manufacturer and supplier in China, we are committed to providing high-quality 2-Chloroethylamine hydrochloride that meets the rigorous demands of these diverse industries. We understand the importance of consistent purity, reliable supply, and competitive pricing. When you search for '2-chloroethylamine hydrochloride manufacturer China' or 'buy cas 870-24-6,' you can trust our expertise and capacity to fulfill your bulk procurement needs.

In conclusion, 2-Chloroethylamine hydrochloride is a compound of immense industrial importance. Its well-defined properties, established synthesis methods, and broad applicability make it an essential chemical intermediate. We encourage you to connect with us for your supply of this critical material, ensuring you receive a high-quality product from a dependable Chinese supplier.