2-Chlorothiazole (CAS: 3034-52-4) is a fundamental heterocyclic compound whose unique chemical properties make it indispensable across multiple industrial sectors. NINGBO INNO PHARMCHEM CO.,LTD., a prominent chemical manufacturer and supplier in China, offers valuable insights into the synthesis, properties, and wide-ranging applications of this essential intermediate.

The synthesis of 2-Chlorothiazole often involves classical routes that have been refined over time. Methods include the reaction of allyl isothiocyanate with chlorinating agents, leading to cyclization and the formation of the thiazole ring. Modern advancements have also introduced catalytic methods, utilizing transition metals like palladium, nickel, or copper, to achieve more efficient and selective synthesis. These catalytic approaches often operate under milder conditions, aligning with green chemistry principles. For a reliable supply, partnering with an experienced chemical manufacturer is key.

Physicochemically, 2-Chlorothiazole is typically described as a clear, colorless to pale yellow liquid. It possesses a distinct, pungent odor. Its molecular formula is C₃H₂ClNS, with a molecular weight of approximately 119.57 g/mol. Key properties include a boiling point around 145-146°C and a flash point of approximately 54°C, classifying it as a flammable liquid. Its solubility in organic solvents, such as ether and ethanol, facilitates its use in various reaction media. Understanding these properties is critical for safe handling and effective utilization, especially when purchasing from a chemical supplier.

The applications of 2-Chlorothiazole are diverse and impactful. In the pharmaceutical industry, it serves as a crucial intermediate for synthesizing active pharmaceutical ingredients (APIs), particularly those targeting conditions like bacterial infections or certain types of cancer. Its thiazole backbone is a common feature in many biologically active molecules. In agrochemicals, it is vital for producing fungicides and herbicides that protect crops and enhance agricultural yields. Furthermore, its characteristic notes make it valuable in the flavor and fragrance industry for creating unique sensory profiles. NINGBO INNO PHARMCHEM CO.,LTD. provides this compound to support these critical industries.

As a leading chemical supplier, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-purity 2-Chlorothiazole (≥98% GC) to meet the exacting demands of our clients. Our commitment to quality assurance, competitive pricing, and a stable supply chain ensures that your research and production needs are met. Whether you are looking to buy for pharmaceutical development, agrochemical formulation, or flavor creation, we are your trusted source.

In conclusion, 2-Chlorothiazole is a cornerstone chemical intermediate whose synthesis, properties, and applications are critical to numerous industries. By understanding these aspects and partnering with a reliable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD., businesses can leverage this compound for innovation and success.