For professionals in the chemical industry, a deep understanding of key intermediates is vital for successful product development and manufacturing. 2-Fluoro-4-nitrophenol, known by its CAS number 403-19-0, is a compound that warrants close attention due to its extensive utility as an organic synthesis intermediate. This article aims to provide a comprehensive overview of its properties, applications, and how to effectively source it from reliable manufacturers.

Technical Specifications and Chemical Properties

2-Fluoro-4-nitrophenol is characterized by its molecular formula C6H4FNO3 and a molecular weight of approximately 157.1 g/mol. It typically appears as an off-white to yellow crystalline powder, with a melting point generally ranging from 117°C to 121°C. Purity is a critical factor, and high-grade material often boasts an assay of ≥98.0% as determined by GC analysis. This level of purity is crucial for its use in demanding synthetic processes. The compound's structure, featuring a phenol group substituted with a fluorine atom at the ortho position and a nitro group at the para position, dictates its chemical reactivity, making it a valuable substrate for various chemical transformations.

Key Applications and Industrial Significance

  • Pharmaceutical Intermediates: Its primary role is as an intermediate in the synthesis of pharmaceuticals. The presence of fluorine and nitro groups allows for targeted modifications to create complex drug molecules with desired therapeutic properties. Pharmaceutical companies often look to buy this intermediate for drug discovery and production.
  • Agrochemical Synthesis: The compound is also utilized in the development of agrochemicals, such as herbicides and pesticides, contributing to more efficient crop protection strategies.
  • Organic Synthesis Reagent: For research laboratories and chemical manufacturers, it serves as a versatile reagent in a wide range of organic reactions, facilitating the creation of novel chemical entities.

Sourcing Strategies: Partnering with China Suppliers

China has established itself as a global hub for chemical manufacturing, offering a competitive edge in the supply of intermediates like 2-Fluoro-4-nitrophenol. Identifying a dependable 2-Fluoro-4-nitrophenol supplier in China is key to ensuring consistent quality and timely delivery. When seeking to purchase this chemical, it is advisable to compare prices from multiple reputable manufacturers and to verify their quality control standards. A strong supplier will provide detailed product specifications, offer flexible packaging options, and be able to scale production to meet your needs, whether for laboratory research or industrial manufacturing. Requesting a detailed quote and inquiring about the availability of samples are essential steps in the sourcing process.

By understanding the technical nuances and strategic sourcing options for 2-Fluoro-4-nitrophenol, R&D scientists and procurement specialists can effectively leverage this important intermediate for their innovative projects.