In the intricate world of organic chemistry and pharmaceutical manufacturing, understanding the precise properties of key intermediates is fundamental. 3-(2-Methoxy-5-methylphenyl)-3-phenylpropan-1-ol, identified by its CAS number 124937-73-1, is one such compound, playing a vital role in the synthesis of important pharmaceutical products, most notably Tolterodine. This article explores its essential chemical and physical characteristics, along with insights into its synthesis and application.

The compound's molecular formula is C17H20O2, with a molecular weight of approximately 256.34 g/mol. Physically, it is often described as a white powder, indicating a solid state at room temperature under standard conditions. Its density is reported around 1.066 g/cm³, and it possesses a relatively high boiling point of 413.8°C at 760 mmHg, suggesting good thermal stability for many chemical processes. The flash point, measured at 184.2°C, is indicative of its flammability characteristics, which are important for safe handling and processing.

The primary application for 3-(2-methoxy-5-methylphenyl)-3-phenylpropan-1-ol is as an intermediate in the production of Tolterodine (CAS: 124937-51-5) and its tartrate salt (CAS: 124937-52-6). Tolterodine is a muscarinic antagonist widely used to treat overactive bladder. The structural features of this intermediate – the specific arrangement of phenyl rings, methoxy groups, and the propanol backbone – make it an ideal precursor for constructing the complex molecule of Tolterodine.

Information regarding its synthesis often points to reduction reactions of related carboxylic acids or other functional groups. For instance, a common method might involve the reduction of 3-(2-methoxy-5-methylphenyl)-3-phenylpropanoic acid using reducing agents like sodium borohydride. Achieving high yields and purity, often exceeding 98%, is a key objective for any efficient synthesis. Manufacturers also emphasize proper storage conditions, recommending sealed, dry environments away from moisture, heat, and strong light to maintain product integrity.

For R&D scientists and procurement managers looking to purchase 3-(2-methoxy-5-methylphenyl)-3-phenylpropan-1-ol, understanding these properties is key to making informed decisions. Identifying a reliable CAS 124937-73-1 supplier, particularly in China, can provide access to high-quality material at competitive prices. When evaluating potential suppliers, look for detailed specifications, robust quality control measures, and a history of consistent supply. Whether for research purposes or large-scale manufacturing, securing this vital intermediate from a trusted source is essential for the success of pharmaceutical development and production.