For professionals in the chemical manufacturing sector, a deep understanding of key intermediates is vital for optimizing production processes and developing new products. 3,5-Dimethylphenylacetic Acid, identified by its CAS number 42288-46-0, is one such compound that warrants close examination due to its industrial significance, particularly as a pharmaceutical intermediate.

Chemical Properties and Characteristics

3,5-Dimethylphenylacetic Acid (molecular formula C10H12O2, molecular weight ~164.20 g/mol) presents as a white to light beige crystalline powder. Its physical form and chemical structure make it amenable to a variety of reactions. The presence of the carboxylic acid group allows for typical reactions such as esterification, amidation, and salt formation, while the dimethyl-substituted phenyl ring offers possibilities for further electrophilic aromatic substitution or modifications at the methyl groups. Its relatively high melting point (typically in the range of 98-102 °C) and stability under standard storage conditions (sealed, dry, room temperature) contribute to its ease of handling and storage in industrial settings. The compound's solubility characteristics, being more soluble in organic solvents than in water, also play a role in its application in various synthesis protocols.

Industrial Applications and Manufacturing Insights

The primary industrial application for 3,5-Dimethylphenylacetic Acid is its use as a crucial intermediate in the pharmaceutical industry. It is an indispensable component in the synthesis pathways of numerous active pharmaceutical ingredients (APIs). Manufacturers leverage its structure to efficiently build complex drug molecules, contributing to the development of treatments across various therapeutic areas. Beyond pharmaceuticals, its utility extends to the broader fine chemical industry, where it can be used in the creation of specialty chemicals, agrochemical intermediates, or materials with unique properties. For manufacturers and bulk purchasers, sourcing this compound from reliable producers, often found in regions like China, is key. These manufacturers typically offer competitive pricing for large volumes and can provide consistent quality, usually at a purity of 99%. Understanding the supply chain, including potential lead times and shipping logistics from major ports, is crucial for effective industrial procurement.

Procurement Considerations for Industrial Use

When looking to buy 3,5-Dimethylphenylacetic Acid for industrial applications, prospective buyers should focus on securing a stable supply of high-quality material. This often means establishing direct relationships with manufacturers rather than relying solely on distributors, especially for significant quantities. Key considerations include verifying the supplier's production capacity, their quality control systems, and their ability to provide necessary documentation such as Certificates of Analysis (CoA). Bulk pricing structures are common, and negotiation around volume discounts can significantly impact the overall cost of production. Furthermore, ensuring that the supplier adheres to relevant safety and environmental regulations is an essential aspect of responsible sourcing. By carefully evaluating these factors, industrial users can secure a dependable and cost-effective supply of 3,5-Dimethylphenylacetic Acid, ensuring the smooth continuation of their manufacturing operations.