3-Methylthiophene, identified by CAS number 616-44-4, is a fundamental organic compound that plays a significant role across various chemical industries. This colorless, transparent liquid is a derivative of thiophene, characterized by a methyl group attached to the third carbon atom of the thiophene ring. Understanding its properties, synthesis, and applications is crucial for procurement managers, R&D scientists, and product formulators.

Physical and Chemical Properties: 3-Methylthiophene is a volatile liquid with a distinct odor. It typically boasts a purity of ≥99.0%. Its physical characteristics include a low melting point of -69 °C and a boiling point around 114-117 °C. It is soluble in most organic solvents but has limited solubility in water. Chemically, it exhibits reactivity typical of thiophene derivatives, participating in electrophilic substitution reactions and serving as a valuable building block in organic synthesis.

Synthesis Routes: While multiple methods exist for synthesizing 3-Methylthiophene, common industrial routes include the cyclization and desulfurization of suitable hydrocarbon precursors, often involving sulfur or sulfur-containing compounds at elevated temperatures. For instance, methods described in Organic Syntheses detail the dry fusion of disodium methylsuccinate with phosphorus heptasulfide. These sophisticated synthesis pathways require precise control and specialized equipment, underscoring the value of sourcing from experienced manufacturers.

Diverse Industrial Applications: The versatility of 3-Methylthiophene is evident in its broad range of applications. It is a key intermediate in the pharmaceutical sector for the synthesis of various drugs. In the agrochemical industry, it is used to produce herbicides and pesticides. Furthermore, its ability to undergo polymerization makes it an important monomer for creating conducting polymers, which are vital for advancements in electronics, sensors, and energy storage technologies.

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