Understanding 3-(tert-Butyldimethylsilyloxy)glutaric Anhydride: Properties and Applications
For chemists and formulators in the B2B chemical space, a deep understanding of intermediate compounds is crucial for successful synthesis and product development. 3-(tert-butyldimethylsilyloxy)glutaric anhydride, identified by CAS number 91424-40-7, is one such compound that merits attention due to its specific chemical characteristics and versatile applications.
Chemically, this compound is an anhydride derived from glutaric acid, featuring a tert-butyldimethylsilyl (TBS) protecting group on the hydroxyl. This silyl ether moiety is known for its stability under various reaction conditions while also being readily cleavable when necessary, making it a valuable protecting group in multi-step organic synthesis. The anhydride functionality offers reactivity for acylations and other related reactions.
The physical properties of 3-(tert-butyldimethylsilyloxy)glutaric anhydride are also important for handling and storage. Typically appearing as white flakes or crystalline powder, it has a melting point in the range of 79-81°C. It's noted to be moisture-sensitive, necessitating storage in tightly-closed containers in a cool, dry, and well-ventilated area away from incompatible substances. Understanding these parameters is vital for any buyer looking to buy 3-(tert-butyldimethylsilyloxy)glutaric anhydride.
The primary application driving demand for this chemical is its role as a key intermediate in the synthesis of pharmaceutical products, most notably Rosuvastatin calcium. This makes it a sought-after material for companies specializing in pharmaceutical intermediates. Therefore, identifying a reliable 3-(tert-butyldimethylsilyloxy)glutaric anhydride manufacturer in China who can guarantee purity and consistency is paramount for R&D scientists and production managers.
When comparing suppliers, buyers often look for competitive cas 91424-40-7 price points. However, it's critical to balance cost with quality assurance from a trustworthy pharmaceutical intermediate supplier. For those actively seeking a rosuvastatin intermediate for sale, working with a manufacturer experienced in pharmaceutical synthesis ensures that all necessary specifications and regulatory requirements are met.
In conclusion, 3-(tert-butyldimethylsilyloxy)glutaric anhydride is a specialized chemical intermediate with defined physical and chemical properties. Its primary application in pharmaceutical synthesis, particularly for statin production, makes it a valuable commodity for research and manufacturing. Diligent sourcing from qualified suppliers is key to leveraging its potential effectively.
Perspectives & Insights
Core Pioneer 24
“Its primary application in pharmaceutical synthesis, particularly for statin production, makes it a valuable commodity for research and manufacturing.”
Silicon Explorer X
“Diligent sourcing from qualified suppliers is key to leveraging its potential effectively.”
Quantum Catalyst AI
“For chemists and formulators in the B2B chemical space, a deep understanding of intermediate compounds is crucial for successful synthesis and product development.”