The world of specialty chemicals is vast and intricate, with each compound playing a unique role in various industrial and research applications. 3-(Trifluoromethyl)pyridin-2-one, identified by CAS number 22245-83-6 and also known as 2-Hydroxy-3-trifluoromethylpyridine, is one such compound that has garnered significant attention in advanced organic synthesis and materials science. For chemical engineers, researchers, and procurement professionals, understanding the characteristics and availability of this trifluoromethyl-substituted pyridine derivative is essential for effective utilization and sourcing.

The chemical profile of 3-(Trifluoromethyl)pyridin-2-one is defined by its molecular structure: a pyridine ring functionalized with both a hydroxyl group (or keto form) and a trifluoromethyl group. This combination results in a compound with distinct electronic and steric properties. Its melting point typically ranges between 150-153°C, and it presents as a white to off-white crystalline powder. These physical attributes are important for handling and formulation. Chemically, the electron-withdrawing trifluoromethyl group influences the reactivity of the pyridine ring, making it a valuable component in regioselective reactions and as a ligand precursor.

While the exact synthesis pathways can be proprietary, general methods often involve fluorination strategies applied to pyridine precursors. For instance, trifluoromethyl iodide in the presence of DMSO and hydrogen peroxide has been cited in literature for its role in such transformations. The efficiency and selectivity of these synthesis methods are critical for manufacturers aiming to produce 3-(Trifluoromethyl)pyridin-2-one at scale and with high purity. When considering a purchase, inquiring about the synthesis route and quality control measures can be beneficial.

The applications of 3-(Trifluoromethyl)pyridin-2-one are diverse, spanning pharmaceutical synthesis, where it acts as a key intermediate for bioactive compounds, to its use as a ligand in homogeneous catalysis. Its ability to form stable complexes with transition metals and impart specific electronic properties makes it a desirable component in catalyst design. Researchers looking to buy this chemical for their projects will find its versatility to be a significant advantage, enabling them to explore new synthetic routes and material properties.

As a global supplier of specialty chemicals, we are committed to providing high-quality 3-(Trifluoromethyl)pyridin-2-one to meet the demands of the scientific community. We understand the importance of purity, consistent supply, and competitive pricing. For any organization seeking to procure this compound, whether for research or industrial applications, we invite you to contact our sales team. Obtain a quote for 2-Hydroxy-3-trifluoromethylpyridine and discover how our reliable supply chain and commitment to quality can support your critical projects.