In the sophisticated landscape of pharmaceutical manufacturing, intermediate compounds play a pivotal role. One such critical intermediate is 4-(2,3-Epoxypropoxy)carbazole, identified by CAS number 51997-51-4. This compound is indispensable for the synthesis of essential medications, making its reliable sourcing and understanding its properties paramount for industry professionals. As a dedicated manufacturer, we offer insights into this vital chemical.

Chemical Identity and Key Properties

4-(2,3-Epoxypropoxy)carbazole, also known by its synonym 4-Glycidyloxycarbazole, possesses the molecular formula C15H13NO2 and a molecular weight of approximately 239.27 g/mol. Its structure features a carbazole ring system functionalized with an epoxypropoxy group. This reactive epoxy moiety is key to its utility in synthesis.

Physically, it typically presents as a pale yellow to almost white powder. Key properties relevant to its handling and application include:

  • Melting Point: 130-132°C
  • Boiling Point: Approximately 464.9°C at 760 mmHg
  • Density: Around 1.327 g/cm³
  • Flash Point: Approximately 166.3°C

These parameters are critical for process design, safety assessments, and quality control when you purchase this compound.

The Imperative of Purity and Specifications

The effectiveness and safety of the final pharmaceutical product heavily depend on the purity of its intermediates. For 4-(2,3-Epoxypropoxy)carbazole, a purity of ≥99% is typically required. Other critical specifications include a low moisture content (≤0.5%) and minimal impurities (≤0.2%), with a low residue on ignition (≤0.1%). These stringent quality standards ensure that the compound will perform reliably in subsequent synthetic steps, such as the production of Carvedilol. As a trusted supplier, we adhere to these rigorous specifications.

Production and Storage Considerations

The synthesis of 4-(2,3-Epoxypropoxy)carbazole involves specific chemical reactions, often starting from 4-Hydroxycarbazole and epichlorohydrin. Manufacturers invest in optimized processes to achieve high yields and purity. For optimal long-term storage, it is typically recommended to keep the compound in a cool, dry, well-closed container, often stored at -20°C, away from moisture and strong light or heat. Proper storage ensures the compound's stability and efficacy when you are ready to use it.

For pharmaceutical companies and research institutions looking to buy this crucial intermediate, partnering with an experienced manufacturer based in regions like China can offer both quality and cost benefits. Engaging with us for a quote will provide access to a reliable source for this essential chemical, supporting your critical production and research needs.