For professionals in the chemical and pharmaceutical industries, understanding the specifics of key intermediates is vital for successful research and production. 4-(4-Methylpiperazin-1-ylmethyl)benzoyl Chloride, identified by CAS number 148077-69-4, stands out as a critical compound with significant applications, particularly as an API intermediate. This article aims to provide an in-depth look at this chemical, offering valuable insights for those looking to buy or research its potential.

Chemical Identity and Properties

4-(4-Methylpiperazin-1-ylmethyl)benzoyl Chloride is an organic compound characterized by its benzoyl chloride functional group and a methylpiperazinyl methyl substituent. Its molecular formula is C13H17ClN2O, with a molecular weight of approximately 252.74 g/mol. Typically supplied as a solid powder, this chemical serves as a reactive intermediate due to the presence of the acid chloride moiety, making it highly useful in acylation reactions. The methylpiperazine group contributes to its solubility and reactivity characteristics, often influencing its application in pharmaceutical synthesis.

Core Applications in Pharmaceutical Synthesis

The primary application of 4-(4-Methylpiperazin-1-ylmethyl)benzoyl Chloride lies in its role as a pharmaceutical intermediate. It is a key building block in the synthesis of various Active Pharmaceutical Ingredients (APIs). Its specific structure allows for the introduction of complex functionalities into target drug molecules, often contributing to their therapeutic efficacy. R&D scientists utilize this compound in multi-step organic synthesis pathways to construct intricate molecular architectures required for modern pharmaceuticals.

When considering its use, procurement managers and research scientists often inquire about its availability and price. Sourcing this intermediate from reliable manufacturers and suppliers, particularly those based in China, can offer significant advantages in terms of cost and consistent supply. Many chemical suppliers offer this compound with high purity levels, often exceeding 98%, which is critical for pharmaceutical-grade synthesis.

Market Insights and Sourcing Considerations

The market for pharmaceutical intermediates is highly competitive, with demand driven by the global pharmaceutical pipeline. Companies looking to buy 4-(4-Methylpiperazin-1-ylmethyl)benzoyl Chloride should focus on identifying manufacturers that demonstrate strong quality control and a stable production capacity. Understanding the typical specifications, such as assay percentage and common impurity profiles, is crucial. For those initiating research or seeking bulk quantities, obtaining a quote from multiple suppliers can help in assessing market prices and identifying the most cost-effective options. A manufacturer's ability to provide detailed technical documentation, like a Material Safety Data Sheet (MSDS) and Certificate of Analysis (CoA), is also a strong indicator of their commitment to quality and transparency.

In summary, 4-(4-Methylpiperazin-1-ylmethyl)benzoyl Chloride (CAS 148077-69-4) is a vital component in the pharmaceutical synthesis toolkit. By understanding its chemical properties and applications, and by partnering with reputable chemical manufacturers and suppliers, R&D scientists and procurement professionals can ensure the efficient and high-quality production of essential medicines.