Understanding 4-Amino-2-bromopyridine: A Guide for Chemical Procurement
For professionals in the chemical and pharmaceutical industries, understanding the sourcing and application of key intermediates is paramount. One such vital compound is 4-Amino-2-bromopyridine, identified by CAS number 7598-35-8. This versatile molecule serves as a critical building block in a wide array of organic synthesis processes, underpinning the development of numerous high-value products.
What is 4-Amino-2-bromopyridine?
Chemically known as 4-Amino-2-bromopyridine, this compound is characterized by its pyridine ring structure, substituted with both an amino group and a bromine atom. Its molecular formula is C5H5BrN2, with a molecular weight of approximately 173.01. Typically, it presents as an off-white to white powder, indicating a high degree of purity essential for its intended applications. Its physical properties, such as a melting point of 92-96°C, make it manageable in laboratory and industrial settings.
The Role in Organic Synthesis
The significance of 4-Amino-2-bromopyridine lies in its bifunctional nature. The bromine atom provides a reactive site for various cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, allowing for the facile introduction of aryl or alkyl groups. Simultaneously, the amino group can participate in amidation, alkylation, or serve as a directing group in further functionalization of the pyridine ring. This dual reactivity makes it an indispensable intermediate for constructing complex molecular architectures.
Applications in Key Industries
The primary utility of 4-Amino-2-bromopyridine is as a pharmaceutical intermediate. It is frequently employed in the synthesis of Active Pharmaceutical Ingredients (APIs) for a broad spectrum of therapeutic areas, including oncology, neurology, and infectious diseases. Researchers leverage its structure to develop novel drug candidates with improved efficacy and targeted action. Beyond pharmaceuticals, it also finds application in the agrochemical sector for the synthesis of advanced pesticides and herbicides, contributing to enhanced crop protection and yield.
Procurement Considerations for B2B Buyers
When sourcing 4-Amino-2-bromopyridine, procurement managers and R&D scientists look for several key attributes: consistent high purity (often ≥99.0%), reliable supply, competitive pricing, and comprehensive technical data. As a leading chemical manufacturer and supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. is committed to meeting these demands. We understand the critical nature of timely delivery and quality assurance for your production schedules and research integrity. By choosing us as your supplier, you gain access to a dependable source for this essential chemical intermediate, enabling you to buy with confidence and streamline your procurement process.
For organizations seeking to buy 4-Amino-2-bromopyridine, exploring options from established manufacturers like ours ensures that you receive a product that meets rigorous specifications, backed by strong customer service and a commitment to building long-term partnerships. We are dedicated to providing efficient solutions for your organic synthesis needs.
Perspectives & Insights
Logic Thinker AI
“This versatile molecule serves as a critical building block in a wide array of organic synthesis processes, underpinning the development of numerous high-value products.”
Molecule Spark 2025
“Chemically known as 4-Amino-2-bromopyridine, this compound is characterized by its pyridine ring structure, substituted with both an amino group and a bromine atom.”
Alpha Pioneer 01
“Typically, it presents as an off-white to white powder, indicating a high degree of purity essential for its intended applications.”