For professionals in the chemical industry, understanding the properties and applications of key intermediates is crucial for successful product development and manufacturing. 4-Chlorothiophenol (CAS 106-54-7) is one such compound, widely recognized for its utility across pharmaceuticals, agrochemicals, and material science. This article aims to provide a detailed overview of 4-Chlorothiophenol, including its essential properties, diverse uses, and guidance on sourcing from reputable manufacturers and suppliers.

What is 4-Chlorothiophenol?
4-Chlorothiophenol, also known by synonyms such as 4-chlorobenzenethiol or p-chlorothiophenol, is an organosulfur compound with the molecular formula C6H5ClS. It is characterized by a benzene ring substituted with a chlorine atom at the para position and a thiol (-SH) group. This specific arrangement of functional groups endows it with unique reactivity, making it a valuable intermediate in organic synthesis.

Key Properties of 4-Chlorothiophenol:
As a high-purity chemical intermediate, 4-Chlorothiophenol typically presents as a white crystalline solid. Its physical and chemical properties are critical for its application:

  • Appearance: White to almost white crystalline solid.
  • Purity: Commonly available with a purity of ≥98% (GC).
  • Melting Point: Typically around 49-51°C.
  • Boiling Point: Approximately 205-207°C.
  • Solubility: Generally insoluble in water but soluble in organic solvents like methanol, ether, and benzene.
  • Reactivity: The thiol group is highly reactive, participating in nucleophilic substitution and metal coordination reactions.

Applications of 4-Chlorothiophenol:
The versatility of 4-Chlorothiophenol leads to its application in several key industries:

  • Pharmaceutical Intermediates: It serves as a critical building block in the synthesis of various APIs, including sulfonamides and enzyme inhibitors, essential for treating a wide range of diseases.
  • Agrochemicals: It is used in the production of pesticides and herbicides, contributing to enhanced crop protection and agricultural productivity.
  • Material Science: Its ability to functionalize surfaces and nanoparticles makes it useful for developing advanced materials, coatings, and sensors.
  • Catalysis: As a ligand, it coordinates with transition metals to facilitate important organic reactions like cross-coupling.

Sourcing 4-Chlorothiophenol:
When looking to buy 4-Chlorothiophenol, it is essential to partner with a reliable manufacturer and supplier. Key considerations include ensuring consistent purity, competitive pricing, and a stable supply chain. As a leading supplier from China, we offer high-quality 4-Chlorothiophenol that meets stringent industry standards. We provide various packaging options and efficient delivery services to meet your specific needs, whether for research and development or large-scale commercial production.

We understand the importance of responsive customer service and technical support. Our team is ready to assist you with inquiries regarding product specifications, safety data sheets, and order placement. By choosing us as your supplier, you gain a trusted partner committed to supporting your chemical sourcing requirements with quality products and competitive 4-Chlorothiophenol prices.

In conclusion, 4-Chlorothiophenol (CAS 106-54-7) is a vital chemical intermediate with broad applicability. By understanding its properties and applications, and by sourcing it from a reputable manufacturer, companies can effectively leverage its potential in their respective industries.