In the realm of organic chemistry and pharmaceutical development, specific chemical intermediates serve as foundational elements for complex synthesis. 4-Cyano-2-methylpyridine (CAS 2214-53-1) is one such vital compound, primarily recognized for its role as an intermediate in the preparation of calcium antagonists. For research scientists and procurement specialists, understanding the chemical profile, applications, and reliable sourcing channels for this compound is essential. This article aims to provide a comprehensive overview of 4-Cyano-2-methylpyridine and guide you on finding quality suppliers and competitive pricing.

Chemical Characteristics of 4-Cyano-2-methylpyridine

The compound, identified by CAS number 2214-53-1, has the molecular formula C7H6N2 and a molecular weight of 118.14. It is categorized as a cyanopyridine and typically presents as a beige solid with a low melting point. Key physical properties include a boiling point of approximately 212.8°C at standard atmospheric pressure and a flash point of 87.2°C. It exhibits good solubility in common organic solvents such as methanol and chloroform, which are frequently used in synthetic procedures. Its molecular structure, featuring a pyridine ring with a nitrile group and a methyl substituent, dictates its reactivity and suitability as a precursor in various chemical transformations.

Primary Application: Pharmaceutical Synthesis

The paramount application of 4-Cyano-2-methylpyridine is its function as a key intermediate in the synthesis of calcium antagonists. These drugs are a cornerstone in the treatment of cardiovascular diseases, including hypertension and angina, by modulating calcium channel activity in the body. The precise synthesis route and final drug efficacy depend heavily on the purity and quality of the intermediates used. Therefore, sourcing high-grade CAS 2214-53-1 is critical for pharmaceutical companies to ensure the safety and effectiveness of their final API products.

Sourcing Strategies for Researchers and Buyers

When planning to purchase 4-Cyano-2-methylpyridine, it is imperative to identify reliable sources. Key considerations for buyers include:

  • Purity and Quality: Always request a Certificate of Analysis (CoA) to verify purity and ensure it meets your project's specifications.
  • Supplier Reliability: Partner with established manufacturers or suppliers with a strong reputation for consistency and timely delivery.
  • Pricing and Volume: Compare pricing from different vendors, especially for bulk orders, to achieve cost efficiencies.
  • Technical Support: Choose suppliers who can offer technical assistance and responsive customer service.

We are a premier manufacturer in China specializing in high-quality pharmaceutical intermediates, including 4-Cyano-2-methylpyridine. We invite researchers and procurement professionals to explore our product catalog, request samples, and obtain quotes. Our commitment is to provide reliable, high-purity chemical intermediates at competitive prices, supporting your critical research and manufacturing needs.