In the realm of fine chemicals and intermediates, understanding the properties and applications of key compounds is crucial for innovation and production. 4-Iodoanisole, identified by its CAS number 696-62-8, is one such versatile molecule that plays a significant role in various chemical synthesis processes. This article aims to provide a detailed look at its characteristics, its widespread applications, and guidance on how to effectively source this important intermediate.

Chemically known as 1-iodo-4-methoxybenzene or p-methoxyiodobenzene, 4-Iodoanisole (C7H7IO) is an aromatic compound with a molecular weight of 234.03. It typically presents as a gray-yellow or off-white to brown powder, with a melting point ranging from 46-53 °C and a boiling point of approximately 237 °C at 760 mmHg. Its solubility in common organic solvents like ethanol, ether, and chloroform, while being practically insoluble in water, dictates its handling and reaction conditions. The compound is also noted to be light-sensitive, necessitating proper storage to maintain its integrity.

The primary value of 4-Iodoanisole lies in its utility as a chemical intermediate. Its iodine atom serves as an excellent handle for a variety of synthetic transformations, particularly palladium-catalyzed cross-coupling reactions. This makes it a fundamental building block in:

  • Pharmaceutical Synthesis: It is extensively used in the development of active pharmaceutical ingredients (APIs) and complex drug molecules, where precise molecular construction is vital.
  • Agrochemicals: It contributes to the synthesis of novel pesticides and herbicides, enhancing crop protection strategies.
  • Specialty Chemicals: Its applications extend to materials science, including the production of liquid crystals, polymers, and other advanced functional materials.
  • Organic Synthesis: It acts as a versatile reagent for creating diverse organic structures in both academic research and industrial applications.

For professionals looking to purchase 4-Iodoanisole, identifying a reliable manufacturer and supplier is a critical step. Many leading chemical suppliers operate out of China, offering high-purity grades of 4-Iodoanisole (e.g., ≥97% or ≥99% purity). When you buy 4-Iodoanisole from such sources, you can expect competitive prices and a dependable supply chain. It is advisable to request detailed product specifications, safety data sheets (SDS), and Certificates of Analysis to ensure the material meets your exact requirements.

Engaging with a reputable 4-Iodoanisole manufacturer allows for access to technical support and potentially custom synthesis services. Whether you require small quantities for R&D or bulk orders for industrial production, a well-established supplier can meet your needs efficiently. By understanding the properties and applications of 4-Iodoanisole, and by choosing a trusted sourcing partner, businesses can effectively leverage this vital chemical intermediate to drive their product development and manufacturing goals forward.