In the realm of chemical manufacturing and research, understanding the properties and proper handling of key intermediates is crucial for success. 4-Methoxybenzyl Chloride (CAS 824-94-2) is one such compound, widely recognized for its utility in pharmaceutical synthesis, organic chemistry, and fine chemical production. As a trusted manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive information and high-quality products to our B2B clientele.

Key Properties and Chemical Behavior of 4-Methoxybenzyl Chloride

4-Methoxybenzyl Chloride is a colorless liquid characterized by its molecular formula C₈H₉ClO and a molecular weight of 156.61 g/mol. Its chemical structure, featuring a benzyl chloride backbone with a methoxy group at the para position, dictates its reactivity. The presence of the methoxy group enhances the electron density of the aromatic ring and stabilizes the benzylic carbocation intermediate formed during nucleophilic substitution reactions. This makes it an effective electrophile for introducing the 4-methoxybenzyl (PMB) group.

Chemists often seek to buy 4-Methoxybenzyl Chloride for its application as a protecting group. The PMB group is particularly valuable for protecting alcohols, amines, and carboxylic acids. It can be readily installed under basic conditions and, importantly, selectively removed using mild oxidative reagents like DDQ or CAN. This characteristic makes it a preferred reagent in multistep syntheses where orthogonality of protecting groups is essential. The ability to purchase high-purity 4-Methoxybenzyl Chloride from a reliable 4-Methoxybenzyl Chloride supplier China like NINGBO INNO PHARMCHEM CO.,LTD. is key to achieving consistent results.

Safe Handling and Storage Recommendations

Like many reactive organic chemicals, 4-Methoxybenzyl Chloride requires careful handling and appropriate storage to maintain its efficacy and ensure safety. It is recommended to store this compound in a cool (2-8°C), dry, and well-ventilated place to prevent degradation. When working with PMB-Cl, it is advisable to use personal protective equipment, including gloves, eye protection, and lab coats, and to conduct operations in a fume hood to avoid inhalation of vapors. Understanding the recommended storage parameters is vital when sourcing this chemical to ensure its stability and optimal performance in your applications.

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NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer committed to delivering high-quality chemical intermediates. We understand the importance of reliable sourcing for your production processes. Our 4-Methoxybenzyl Chloride (CAS 824-94-2) is produced to stringent purity standards, ensuring consistent performance in your synthetic endeavors. By partnering with us, you benefit from competitive CAS 824-94-2 price points and a dependable supply chain. We are your go-to 4-Methoxybenzyl Chloride manufacturer for all your pharmaceutical and fine chemical needs. Contact us to inquire about bulk orders and specific product requirements.