Understanding 4-Methylbenzenesulfonhydrazide: From Synthesis to Industrial Use
4-Methylbenzenesulfonhydrazide (CAS 1576-35-8), often referred to as p-Toluenesulfonhydrazide or Tosylhydrazide, is a chemical compound that plays a crucial role in various synthetic processes. Understanding its synthesis, properties, and applications is key for chemists and procurement specialists looking to source reliable chemical intermediates. This white crystalline solid is a cornerstone in organic synthesis, particularly for creating complex molecular structures used in pharmaceuticals and fine chemicals.
The synthesis of 4-Methylbenzenesulfonhydrazide typically involves reacting p-toluenesulfonyl chloride with hydrazine hydrate under controlled conditions. This method, refined over time by manufacturers, ensures a high yield and purity of the final product, often reaching 98% or more. For those in the industry, particularly in pharmaceutical and specialty chemical manufacturing, the ability to buy this intermediate from a consistent and quality-focused supplier is essential. The compound's physical form as a powder facilitates its handling in laboratory and industrial settings.
Key to its utility is its reactivity, primarily in the formation of tosylhydrazones. This process involves the condensation reaction with carbonyl compounds (aldehydes and ketones). Tosylhydrazones are pivotal intermediates in several important organic transformations, such as the Shapiro reaction for generating vinyl anions and the Bamford-Stevens reaction for alkene synthesis. These reactions are fundamental in building complex carbon skeletons, making 4-Methylbenzenesulfonhydrazide an indispensable tool for synthetic chemists. Researchers frequently search for suppliers to buy this reagent for their synthesis projects.
Beyond these core applications, the compound also finds use in the cosmetic industry and as a general intermediate in pharmaceutical synthesis. Its versatility means that manufacturers across various sectors rely on its availability. As a leading supplier from China, we are committed to providing high-quality 4-Methylbenzenesulfonhydrazide that meets stringent industry standards. Our focus on quality control and a stable supply chain ensures that our customers can confidently purchase this essential chemical.
For businesses and researchers seeking to purchase 4-Methylbenzenesulfonhydrazide, understanding the product's specifications, purity, and the reliability of the supplier is critical. We offer this valuable intermediate with guaranteed purity and competitive pricing, making it an accessible resource for a wide range of applications. We encourage you to contact us to discuss your specific needs and learn how our 4-Methylbenzenesulfonhydrazide can contribute to your synthesis objectives and manufacturing processes.
Perspectives & Insights
Logic Thinker AI
“Researchers frequently search for suppliers to buy this reagent for their synthesis projects.”
Molecule Spark 2025
“Beyond these core applications, the compound also finds use in the cosmetic industry and as a general intermediate in pharmaceutical synthesis.”
Alpha Pioneer 01
“Its versatility means that manufacturers across various sectors rely on its availability.”