Understanding 5-Methyluridine (CAS 1463-10-1): A Key Pharma Intermediate
For professionals in the pharmaceutical and chemical industries, understanding the precise specifications and applications of key intermediates is vital for successful product development and manufacturing. 5-Methyluridine, also known as Ribothymidine, is one such critical compound, playing an indispensable role in the synthesis of important therapeutic agents, most notably Zidovudine (AZT).
With the Chemical Abstracts Service (CAS) registry number 1463-10-1, Ribothymidine is chemically defined as 1-\[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione. Its molecular formula is C10H14N2O6, with a molecular weight of 258.22800. Typically, this intermediate presents as a white to off-white crystalline powder, a common characteristic for highly purified organic compounds. Key specifications that purchasers often scrutinize include the assay, which should be high (≥98.0% by HPLC), and parameters like loss on drying (≤0.5%) and residue on ignition (≤0.5%), which indicate minimal impurities and volatile content.
The primary application driving the demand for 5-Methyluridine is its use as an intermediate in the production of Zidovudine, an antiretroviral drug that has been instrumental in managing HIV infections. The efficacy and safety of Zidovudine are directly dependent on the quality of its precursors. Therefore, sourcing Ribothymidine from reliable manufacturers, especially those in China renowned for their quality control and production capacity, is a strategic imperative for pharmaceutical companies worldwide. When you decide to buy 5-Methyluridine, choosing a trusted supplier ensures that your synthesis process is robust and that your final API meets all stringent regulatory requirements.
As a dedicated supplier, we aim to provide comprehensive support to our clients, offering not just high-quality 5-Methyluridine but also competitive pricing and responsive customer service. Understanding the needs of the pharmaceutical market, we are committed to being a stable and dependable source for this crucial intermediate. We encourage procurement specialists and R&D scientists to consider our offerings for their needs, ensuring a seamless procurement process.
Perspectives & Insights
Chem Catalyst Pro
“Key specifications that purchasers often scrutinize include the assay, which should be high (≥98.”
Agile Thinker 7
“The primary application driving the demand for 5-Methyluridine is its use as an intermediate in the production of Zidovudine, an antiretroviral drug that has been instrumental in managing HIV infections.”
Logic Spark 24
“The efficacy and safety of Zidovudine are directly dependent on the quality of its precursors.”