For professionals in the chemical and pharmaceutical industries, understanding the properties and sourcing channels for key intermediates is vital. 5-Pyrimidinemethanol, identified by its CAS number 25193-95-7, is one such compound that warrants close examination. This article delves into its essential characteristics and provides guidance on how to procure it from reliable sources.

5-Pyrimidinemethanol is a heterocyclic organic compound with the molecular formula C5H6N2O and a molecular weight of approximately 110.11 g/mol. It typically presents as a yellow solid with a melting point around 51-52°C and a boiling point of approximately 250.8°C. Its structure features a pyrimidine ring substituted with a hydroxymethyl group, imparting it with chemical reactivity valuable in organic synthesis. The compound is soluble in polar solvents, facilitating its use in various reaction media.

The primary applications of 5-Pyrimidinemethanol lie in its role as a pharmaceutical intermediate. It is critically involved in the synthesis of melanin-concentrating hormone receptor 1 antagonists, a class of compounds being investigated for metabolic and appetite regulation. Beyond this, it serves as a building block for constructing complex annulated pyridines, which are common motifs in many biologically active molecules. When you are looking to buy this chemical, understanding these applications helps in appreciating its significance.

Sourcing 5-Pyrimidinemethanol can involve searching for '5-Pyrimidinemethanol price manufacturer' or 'pharmaceutical intermediate supplier China'. China has emerged as a significant global hub for chemical manufacturing, offering competitive pricing and a wide array of suppliers. When engaging with a supplier, it is prudent to request detailed technical data, including purity specifications (often a minimum of 97%) and information on manufacturing processes. Access to a manufacturer's expertise can also be invaluable.

For those requiring bulk quantities or specific formulations, working directly with a manufacturer can ensure better control over quality and supply chain. Companies that offer custom synthesis services can also be an excellent resource if standard grades do not meet specific project requirements. Ultimately, a successful procurement strategy for 5-Pyrimidinemethanol involves diligent research into potential suppliers, comparing pricing, and prioritizing consistent quality and reliable delivery.