Understanding 6-Bromo-2,2'-bipyridine: Properties and Synthesis for R&D
For chemists engaged in research and development, a thorough understanding of the properties and synthesis pathways of key intermediates is fundamental. 6-Bromo-2,2'-bipyridine (CAS 10495-73-5) stands out as a versatile molecule with significant potential across various scientific disciplines, from advanced materials to pharmaceutical synthesis. Procurement professionals and R&D scientists often seek detailed information on its characteristics and how to efficiently buy it from reliable sources, particularly from leading manufacturers in China.
Physically, 6-Bromo-2,2'-bipyridine is typically described as a white to almost white crystalline powder. Its melting point falls within the range of 72.0 to 76.0 °C, indicating it is a stable solid at room temperature. Chemically, it possesses a molecular formula of C10H7BrN2 and a molecular weight of 235.08 g/mol. The presence of the bromine atom makes it highly reactive in various cross-coupling reactions, such as palladium-catalyzed C-C bond formations, which are cornerstones of modern organic synthesis. This reactivity allows for the facile introduction of diverse functional groups, enabling the construction of complex molecular architectures relevant to drug discovery and the development of new functional materials.
The synthesis of 6-Bromo-2,2'-bipyridine typically involves palladium-catalyzed cross-coupling reactions. A common method reported in literature uses 2,6-dibromopyridine and a stannylpyridine derivative, followed by purification steps such as column chromatography. While synthesis in-house is an option for some research groups, the complexity and cost-effectiveness often make it more practical to purchase this intermediate from specialized chemical suppliers. For those looking for a consistent and high-purity source, exploring the extensive network of suppliers in China is a prudent step. These manufacturers can provide this compound with a minimum purity of 99%, ensuring reliability for demanding R&D applications.
When you are ready to procure 6-Bromo-2,2'-bipyridine for your research, consider factors like batch-to-batch consistency, detailed analytical data (such as NMR and HPLC), and responsive customer service. Engaging with established chemical suppliers in China can offer competitive prices and dependable availability, supporting your ongoing research endeavors. Whether you are synthesizing novel OLED materials or exploring new pharmaceutical candidates, securing this key intermediate from a trusted source will be pivotal to your project's success.
Perspectives & Insights
Agile Reader One
“Whether you are synthesizing novel OLED materials or exploring new pharmaceutical candidates, securing this key intermediate from a trusted source will be pivotal to your project's success.”
Logic Vision Labs
“For chemists engaged in research and development, a thorough understanding of the properties and synthesis pathways of key intermediates is fundamental.”
Molecule Origin 88
“6-Bromo-2,2'-bipyridine (CAS 10495-73-5) stands out as a versatile molecule with significant potential across various scientific disciplines, from advanced materials to pharmaceutical synthesis.”