In the dynamic world of chemical synthesis, specific intermediates play pivotal roles in unlocking new frontiers in pharmaceuticals, materials science, and electronics. Among these, 6-Fluoroindole (CAS 399-51-9) stands out as a particularly valuable fluorinated building block. Its unique structure and reactivity make it an indispensable component for researchers and manufacturers aiming to develop next-generation products.

What is 6-Fluoroindole?

6-Fluoroindole, identified by its CAS number 399-51-9, is a heterocyclic organic compound. It is characterized by an indole core structure with a fluorine atom attached at the 6th position of the benzene ring. This fluorination significantly alters its electronic properties and reactivity compared to its non-fluorinated counterpart. The compound typically appears as a beige-brown crystalline powder, with a melting point ranging from 72-76 °C. Its chemical formula is C8H6FN, and its molecular weight is approximately 135.14 g/mol.

Applications Driving Demand

The versatility of 6-Fluoroindole is evident in its wide array of applications:

  • Pharmaceutical Intermediates: This is perhaps the most significant application. 6-Fluoroindole serves as a crucial synthesis intermediate for a variety of bioactive compounds. It is used in the development of potential anticancer immunomodulators, specifically in the synthesis of tryptophan dioxygenase inhibitors like pyridyl-ethenyl-indoles. Furthermore, its structural features make it valuable for creating selective serotonin reuptuptake inhibitors (SSRIs) and inhibitors of HIV-1 attachment, highlighting its importance in drug discovery and development pipelines. For those looking to buy high-purity 6-fluoroindole for pharmaceutical synthesis, NINGBO INNO PHARMCHEM CO.,LTD. is a reliable manufacturer in China.
  • OLED and Semiconductor Materials: The incorporation of fluorine atoms into organic molecules often imparts unique electronic and photophysical properties. Consequently, 6-Fluoroindole is employed in the synthesis of advanced materials for Organic Light-Emitting Diodes (OLEDs) and semiconductor applications. Its use in these fields contributes to the development of more efficient and durable electronic devices. Manufacturers seeking specialized materials for electronics can find reputable suppliers for this chemical.
  • Fluorinated Compounds and Research: Beyond specific end-product applications, 6-Fluoroindole is a fundamental building block for synthesizing a broad spectrum of novel fluorinated organic compounds. These compounds are of great interest in academic and industrial research for various applications, including agrochemicals and materials science.

Sourcing High-Quality 6-Fluoroindole

For researchers and manufacturers, securing a consistent supply of high-purity 6-Fluoroindole is paramount. As a leading chemical supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-quality intermediates like 6-Fluoroindole. We understand the critical nature of these materials for your projects. Whether you are looking for small quantities for R&D or bulk orders for production, our company offers competitive pricing and ensures stringent quality control. To inquire about purchasing 6-fluoroindole or to request a quote, consider reaching out to experienced manufacturers in China who can meet your specific requirements.

In summary, 6-Fluoroindole is more than just a chemical compound; it is an enabler of innovation. Its role as a pharmaceutical intermediate and its utility in advanced materials underscore its significance in modern chemical industries. Partnering with a reliable manufacturer for your chemical sourcing needs will ensure the success of your research and production endeavors.